Satoshi Shimizu

Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by Bcl-2 and Bcl-XL.

Satoshi Shimizu, Yawara Eguchi, Wataru Kamiike et al. · PubMed · 1996 · 362 citations

Apoptosis, Immunology, Pathology +17

The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma

Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita et al. · Journal of Hepatology · 2010 · 342 citations

Tumor Biology, Sorafenib-induced Apoptosis, Human Hepatocellular Carcinoma +13

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita et al. · International Journal of Cancer · 2011 · 259 citations

Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.

Satoshi Shimizu, Yawara Eguchi, Wataru Kamiike et al. · PubMed · 1996 · 257 citations

Phase I study of sorafenib in Japanese patients with hepatocellular carcinoma

Junji Furuse, Hiroshi Ishii, Kohei Nakachi et al. · Cancer Science · 2007 · 193 citations · Full text