Wataru Kamiike

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

Shigeomi Shimizu, Yutaka Eguchi, Hiroaki Kosaka et al. · Nature · 1995 · 614 citations

Life Sciences, Cell Biology, Molecular Medicine +10

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

Shigeomi Shimizu, Yutaka Eguchi, Wataru Kamiike et al. · Proceedings of the National Academy of Sciences · 1998 · 414 citations

Life Sciences, Biochemistry, Cell Biology +11

Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by Bcl-2 and Bcl-XL.

Satoshi Shimizu, Yawara Eguchi, Wataru Kamiike et al. · PubMed · 1996 · 362 citations

Life Sciences, Cancer Biology, Cell Biology +14

Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors.

Shigeomi Shimizu, Yawara Eguchi, Wataru Kamiike et al. · PubMed · 1996 · 300 citations

Life Sciences, Cell Biology, Pharmacology +14

Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.

Satoshi Shimizu, Yawara Eguchi, Wataru Kamiike et al. · PubMed · 1996 · 257 citations

Life Sciences, Biochemistry, Cell Biology +12