Concepedia

Bayesian Interim Monitoring

Bayesian Interim Monitoring is a statistical methodology within Bayesian clinical trial design that enables repeated evaluation of accumulating evidence during the trial to assess efficacy, futility, or safety, using posterior or predictive probabilities to inform stopping decisions while maintaining probabilistic coherence.

32

Publications

2.3K

Citations

96

Authors

61

Institutions

Publications per year

2017–2026

6

Variants

Bayesian Interim Analysis

Parents

Publications

32

Bayesian Approaches to Randomized Trials

David J. Spiegelhalter, Laurence S. Freedman, Mahesh Parmar · Journal of the Royal Statistical Society Series A (Statistics in Society) · 1994 · 728 citations

, , +16

The utility of Bayesian predictive probabilities for interim monitoring of clinical trials

Benjamin R. Saville, Jason T. Connor, Gregory D. Ayers et al. · Clinical Trials · 2014 · 170 citations · Full text

, , +14

Bayesian predictive approach to interim monitoring in clinical trials

Alexei Dmitrienko, Ming‐Dauh Wang · Statistics in Medicine · 2005 · 131 citations

, , +16

Stopping rules and estimation problems in clinical trials

Michael D. Hughes, Stuart Pocock · Statistics in Medicine · 1988 · 129 citations

, , +16

TUTORIAL IN BIOSTATISTICS: BAYESIAN DATA MONITORING IN CLINICAL TRIALS

Peter Fayers, Deborah Ashby, Mahesh Parmar · Statistics in Medicine · 1997 · 119 citations

, , +11

1–5 of 32

Authors

96

  1. MP
    Mahesh Parmar

    University College London, United Kingdom

    5 publications · 1.1K citations

    5

    h-index

  2. DJ
    David J. Spiegelhalter

    MRC Biostatistics Unit, United Kingdom

    4 publications · 962 citations

    4

    h-index

  3. LS
    Laurence S. Freedman

    Sheba Medical Center, Israel

    4 publications · 950 citations

    4

    h-index

  4. BP
    Bradley P. Carlin

    University of Minnesota, United States

    3 publications · 162 citations

    3

    h-index

  5. DA
    Deborah Ashby

    Imperial College London, United Kingdom

    2 publications · 139 citations

    2

    h-index

1–5 of 96

Institutions

61

  1. University of Minnesota

    Minneapolis, United States

    4 h-index

    5 publications

    203 citations

  2. National Cancer Institute

    Bethesda, United States

    3 h-index

    5 publications

    874 citations

  3. MRC Biostatistics Unit

    Cambridge, United Kingdom

    3 h-index

    3 publications

    234 citations

  4. Eli Lilly (United States)

    Indianapolis, United States

    3 h-index

    5 publications

    346 citations

  5. The University of Texas Health Science Center at Houston

    Houston, United States

    2 h-index

    3 publications

    122 citations

  6. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    5 publications

    149 citations

  7. Kyoto University

    Kyoto, Japan

    1 h-index

    1 publications

    12 citations

  8. VA Connecticut Healthcare System

    West Haven, United States

    1 h-index

    3 publications

    48 citations

1–8 of 61

Venues

  1. Statistics in Medicine

    12 publications · 823 citations

    10

    h-index

  2. Journal of Biopharmaceutical Statistics

    JBS · 2 publications · 108 citations

    2

    h-index

  3. Trials

    2 publications · 60 citations

    2

    h-index

  4. JNCI Journal of the National Cancer Institute

    1 publications · 27 citations

    1

    h-index

  5. Biometrical Journal

    1 publications · 28 citations

    1

    h-index

1–5