Concepedia

Backbone Pseudorotation

Backbone Pseudorotation is a conformational dynamics phenomenon in nucleic acid chemistry wherein the sugar-phosphate backbone undergoes a concerted, periodic rearrangement of torsional angles, distinct from classical rotation, that redistributes substituent positions without breaking covalent bonds.

53

Publications

4.4K

Citations

150

Authors

56

Institutions

Publications per year

2017–2026

0

Parents

Publications

53

Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

C. Altona, M. Sundaralingam · Journal of the American Chemical Society · 1972 · 2.1K citations

, , +13

Empirical Correlations Between Conformational Parameters in β‐D‐Furanoside Fragments Derived from a Statistical Survey of Crystal Structures of Nucleic Acid Constituents Full Description of Nucleoside Molecular Geometries in Terms of Four Parameters

Harry P. M. de Leeuw, C. A. G. Haasnoot, C. Altona · Israel Journal of Chemistry · 1980 · 229 citations

, , +17

The relationship between proton–proton NMR coupling constants and substituent electronegativities. II—conformational analysis of the sugar ring in nucleosides and nucleotides in solution using a generalized Karplus equation

C. A. G. Haasnoot, Frank A.A.M. de Leeuw, Harry P. M. de Leeuw et al. · Organic Magnetic Resonance · 1981 · 219 citations

, , +15

How do the gauche and anomeric effects drive the pseudorotational equilibrium of the pentofuranose moiety of nucleosides?

Janez Plavec, Weimin Tong, Jyoti Chattopadhyaya · Journal of the American Chemical Society · 1993 · 211 citations

, , +9

Relationship between proton–proton nmr coupling constants and substituent electronegativities. III. Conformational analysis of proline rings in solution using a generalized Karplus equation

C. A. G. Haasnoot, Frank A.A.M. de Leeuw, Harry P. M. de Leeuw et al. · Biopolymers · 1981 · 132 citations

, , +17

1–5 of 53

Authors

150

  1. HP
    Harry P. M. de Leeuw

    Leiden University, Netherlands

    3 publications · 580 citations

    3

    h-index

  2. CA
    C. Altona

    Leiden University, Netherlands

    3 publications · 570 citations

    3

    h-index

  3. JP
    Janez Plavec

    National Institute of Chemistry, Slovenia

    3 publications · 318 citations

    3

    h-index

  4. FA
    Frank A.A.M. de Leeuw

    National Institute for Public Health and the Environment, Netherlands

    3 publications · 473 citations

    3

    h-index

  5. CA
    C. A. G. Haasnoot

    Radboud University Nijmegen, Netherlands

    3 publications · 580 citations

    3

    h-index

1–5 of 150

Institutions

56

  1. Leiden University

    Leiden, The Netherlands

    4 h-index

    13 publications

    2.2K citations

  2. Virginia Tech

    Blacksburg, United States

    2 h-index

    7 publications

    90 citations

  3. Freie Universität Berlin

    Berlin, Germany

    2 h-index

    7 publications

    159 citations

  4. California Institute of Technology

    Pasadena, United States

    2 h-index

    4 publications

    320 citations

  5. Connecticut Agricultural Experiment Station

    New Haven, United States

    1 h-index

    1 publications

    57 citations

  6. University of Bremen

    Bremen, Germany

    1 h-index

    5 publications

    65 citations

  7. Université Claude Bernard Lyon 1

    Villeurbanne, France

    1 h-index

    2 publications

    48 citations

  8. Taras Shevchenko National University of Kyiv

    Kyiv, Ukraine

    1 h-index

    2 publications

    102 citations

1–8 of 56

Venues

  1. Journal of the American Chemical Society

    JACS · 9 publications · 2.7K citations

    9

    h-index

  2. Chemical Physics Letters

    5 publications · 170 citations

    5

    h-index

  3. 3

    h-index

  4. Theoretical Chemistry Accounts

    2 publications · 37 citations

    2

    h-index

  5. Biopolymers

    2 publications · 148 citations

    2

    h-index

1–5