Concepedia

Backbone Chemistry

Backbone Chemistry is a subfield of Nucleic Acid Chemistry that focuses on the chemical structure, modification, and reactivity of the phosphate-sugar framework that forms the structural core of nucleic acid polymers, distinguishing it from studies centered on nucleobase interactions or sequence-specific functions.

646

Publications

29.9K

Citations

2.2K

Authors

561

Institutions

Publications per year

2017–2026

64

Parents

Children

Publications

646

Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

C. Altona, M. Sundaralingam · Journal of the American Chemical Society · 1972 · 2.1K citations

, , +13

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 736 citations

, , +12

Effect of sulfonic acid group on polyaniline backbone

Zhao H. Wang, K.R. Cromack, Arthur J. Epstein et al. · Journal of the American Chemical Society · 1991 · 631 citations

, , +8

Hypochromism in Polynucleotides<sup>1</sup>

Ignacio Tinoco · Journal of the American Chemical Society · 1960 · 512 citations

, , +5

Two-dimensional NMR spectroscopy reveals cation-triggered backbone degradation in polysulfone-based anion exchange membranes

Christopher G. Arges, Vijay Ramani · Proceedings of the National Academy of Sciences · 2013 · 482 citations · Full text

, , +17

1–5 of 646

Authors

2.2K

  1. VA
    Vaijayanti A. Kumar

    National Chemical Laboratory, India

    10 publications · 288 citations

    10

    h-index

  2. KN
    Krishna N. Ganesh

    National Chemical Laboratory, India

    9 publications · 263 citations

    9

    h-index

  3. MB
    Marianne Bäudler

    University of Cologne, Germany

    8 publications · 745 citations

    8

    h-index

  4. AD
    Alain De Mesmaeker

    Novartis (Switzerland), Switzerland

    7 publications · 150 citations

    7

    h-index

  5. AW
    Adrian Waldner

    Novartis (Switzerland), Switzerland

    5 publications · 124 citations

    5

    h-index

1–5 of 2.2K

Institutions

561

  1. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    107 publications

    2.6K citations

  2. National Chemical Laboratory

    Pune, India

    13 h-index

    35 publications

    942 citations

  3. Rutgers, The State University of New Jersey

    New Brunswick, United States

    10 h-index

    24 publications

    1.7K citations

  4. Novartis (Switzerland)

    Basel, Switzerland

    10 h-index

    38 publications

    971 citations

  5. National Institutes of Health

    Bethesda, United States

    9 h-index

    29 publications

    1.4K citations

  6. Duke University

    Durham, United States

    9 h-index

    22 publications

    866 citations

  7. ETH Zurich

    Zurich, Switzerland

    9 h-index

    30 publications

    796 citations

  8. University of Cologne

    Cologne, Germany

    8 h-index

    20 publications

    1.2K citations

1–8 of 561

Venues

  1. Journal of the American Chemical Society

    JACS · 103 publications · 9.6K citations

    43

    h-index

  2. The Journal of Organic Chemistry

    JOC · 45 publications · 1.4K citations

    26

    h-index

  3. Biochemistry

    24 publications · 1.2K citations

    20

    h-index

  4. Journal of Biomolecular NMR

    22 publications · 641 citations

    16

    h-index

  5. Tetrahedron Letters

    19 publications · 555 citations

    15

    h-index

1–5