Concepedia

Avidity Engineering

Avidity Engineering is a methodological framework within yeast display technology that enhances the functional affinity of molecular interactions by optimizing multivalent binding architectures between displayed receptors and their targets.

5

Publications

199

Citations

35

Authors

11

Institutions

Publications per year

2017–2026

3

Parents

Publications

5

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

Clifford M. Csizmar, Jacob Petersburg, Thomas J. Perry et al. · Journal of the American Chemical Society · 2018 · 103 citations · Full text

, , +17

Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression

Chungyong Han, Su-Jung Sim, Seon-Hee Kim et al. · Nature Communications · 2018 · 38 citations · Full text

, , +17

Monitoring Antigen‐Specific T Cells Using <scp>MHC</scp>‐<scp>Ig</scp> Dimers

Jonathan P. Schneck, Jill E. Slansky, Sean M. O’Herrin et al. · Current Protocols in Immunology · 2000 · 33 citations

, , +17

Titrating Avidity of Yeast-Displayed Proteins Using a Transcriptional Regulator

Joanan López-Morales, Rosario Vanella, Gordana Kovačević et al. · ACS Synthetic Biology · 2023 · 13 citations · Full text

, , +14

Recombinant antibody-metallothionein: design and evaluation for radioimmunoimaging.

Chhaya Das, P. V. Kulkarni, A Constantinescu et al. · Proceedings of the National Academy of Sciences · 1992 · 13 citations

, , +17

1–5 of 5

Authors

35

  1. JP
    Jacob Petersburg

    University of Minnesota, United States

    1 publications · 103 citations

    1

    h-index

  2. CR
    Christoph Rader

    Scripps Research Institute, United States

    1 publications · 12 citations

    1

    h-index

  3. SM
    Sean M. O’Herrin

    Johns Hopkins University, United States

    1 publications · 33 citations

    1

    h-index

  4. SK
    Seon-Hee Kim

    National Cancer Center, South Korea

    1 publications · 38 citations

    1

    h-index

  5. CD
    Chhaya Das

    The University of Texas at Austin, United States

    1 publications · 13 citations

    1

    h-index

1–5 of 35

Institutions

11

  1. National Cancer Institute

    Bethesda, United States

    1 h-index

    3 publications

    36 citations

  2. National Institutes of Health

    Bethesda, United States

    1 h-index

    3 publications

    36 citations

  3. Eilenburger Elektrolyse - und Umwelttechnik (Germany)

    Eilenburg, Germany

    1 h-index

    1 publications

    38 citations

  4. Scripps Research Institute

    San Diego, United States

    1 h-index

    2 publications

    24 citations

  5. National Cancer Center

    Goyang-si, South Korea

    1 h-index

    11 publications

    418 citations

  6. The University of Texas Southwestern Medical Center

    Dallas, United States

    1 h-index

    6 publications

    78 citations

  7. Tulane University

    New Orleans, United States

    1 h-index

    1 publications

    38 citations

  8. Center for Cancer Research

    Bethesda, United States

    1 h-index

    3 publications

    36 citations

1–8 of 11

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 13 citations

    1

    h-index

  2. Nature Communications

    1 publications · 38 citations

    1

    h-index

  3. Journal of the American Chemical Society

    JACS · 1 publications · 103 citations

    1

    h-index

  4. Frontiers in Immunology

    1 publications · 12 citations

    1

    h-index

  5. Current Protocols in Immunology

    1 publications · 33 citations

    1

    h-index

1–5