Concepedia

Antigen-antibody Interface Analysis

Antigen-Antibody Interface Analysis is a computational and structural biology method that characterizes the precise molecular interactions at the binding site between an antigen and an antibody, distinguishing it from broader epitope mapping techniques by focusing specifically on the atomic-level contact residues and physicochemical forces stabilizing the immune complex.

96

Publications

6.3K

Citations

519

Authors

190

Institutions

Publications per year

2017–2026

26

Parents

Publications

96

Antibody-antigen Interactions: Contact Analysis and Binding Site Topography

Robert M. MacCallum, Andrew C.R. Martin, Janet M. Thornton · Journal of Molecular Biology · 1996 · 473 citations

, , +16

A New Clustering of Antibody CDR Loop Conformations

Benjamin North, Andreas Lehmann, Roland L. Dunbrack · Journal of Molecular Biology · 2010 · 402 citations

, , +14

Amplification of antigen–antibody interactions based on biotin labeled protein–streptavidin network complex using impedance spectroscopy

Renjun Pei, Zhiliang Cheng, Erkang Wang et al. · Biosensors and Bioelectronics · 2001 · 249 citations

, , +16

Epitope Mapping by Label-Free Biomolecular Interaction Analysis

Magnus Malmqvist · Methods · 1996 · 223 citations

, , +14

High resolution functional analysis of antibody-antigen interactions

Lei Jin, B M Fendly, James A. Wells · Journal of Molecular Biology · 1992 · 213 citations

, , +14

1–5 of 96

Authors

519

  1. YL
    Yili Li

    Advanced Bioscience Laboratories (United States), United States

    3 publications · 242 citations

    3

    h-index

  2. RA
    Roy A. Mariuzza

    Biotechnology Institute, United States

    3 publications · 290 citations

    3

    h-index

  3. SJ
    Sandra J. Smith‐Gill

    National Cancer Institute, United States

    3 publications · 242 citations

    3

    h-index

  4. AC
    Andrew C.R. Martin

    University College London, United Kingdom

    2 publications · 560 citations

    2

    h-index

  5. TY
    Takefumi Yamashita

    The University of Tokyo, Japan

    2 publications · 56 citations

    2

    h-index

1–5 of 519

Institutions

190

  1. National University of Singapore

    Singapore, Singapore

    4 h-index

    14 publications

    409 citations

  2. University College London

    London, United Kingdom

    3 h-index

    7 publications

    1.7K citations

  3. National Institutes of Health

    Bethesda, United States

    3 h-index

    19 publications

    1.8K citations

  4. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    11 publications

    1.1K citations

  5. National Cancer Institute

    Bethesda, United States

    3 h-index

    19 publications

    2K citations

  6. Institut Pasteur

    Paris, France

    2 h-index

    17 publications

    1.4K citations

  7. Novartis Institutes for BioMedical Research

    Basel, Switzerland

    2 h-index

    5 publications

    335 citations

  8. Center for Drug Evaluation and Research

    Silver Spring, United States

    2 h-index

    19 publications

    2.2K citations

1–8 of 190

Venues

  1. Journal of Molecular Biology

    JMB · 8 publications · 1.3K citations

    8

    h-index

  2. Bioinformatics

    5 publications · 350 citations

    5

    h-index

  3. Journal of Biological Chemistry

    JBC · 4 publications · 266 citations

    4

    h-index

  4. Molecular Immunology

    4 publications · 188 citations

    4

    h-index

  5. mAbs

    4 publications · 224 citations

    4

    h-index

1–5