Concepedia

Antigen Interaction Modeling

Antigen Interaction Modeling is a computational or theoretical framework within protein-protein interaction modeling that specifically characterizes the molecular binding mechanisms and structural dynamics between antigens and their interacting partners, such as antibodies or immune receptors.

62

Publications

2.9K

Citations

220

Authors

111

Institutions

Publications per year

2017–2026

16

Parents

Publications

62

Calculations of antibody-antigen interactions: microscopic and semi-microscopic evaluation of the free energies of binding of phosphorylcholine analogs to McPC603

Zhen-Tao Chu, Michael B. Bolger, Arieh Warshel · Protein Engineering Design and Selection · 1992 · 313 citations

, , +17

Minimal Model for the Mechanism of Antibody Induction and Paralysis by Antigen

Peter A. Bretscher, Melvin Cohn · Nature · 1968 · 160 citations

, , +12

Learning context-aware structural representations to predict antigen and antibody binding interfaces

Srivamshi Pittala, Chris Bailey‐Kellogg · Bioinformatics · 2020 · 150 citations · Full text

, , +17

Evaluation of <scp>AlphaFold</scp> antibody–antigen modeling with implications for improving predictive accuracy

Rui Yin, Brian G. Pierce · Protein Science · 2023 · 128 citations · Full text

, , +15

IgLM: Infilling language modeling for antibody sequence design

Richard W. Shuai, Jeffrey A. Ruffolo, Jeffrey J. Gray · Cell Systems · 2023 · 124 citations · Full text

, , +14

1–5 of 62

Authors

220

  1. DR
    Darren R. Flower

    Jenner Institute, United Kingdom

    6 publications · 371 citations

    6

    h-index

  2. CM
    Charlotte M. Deane

    University of Oxford, United Kingdom

    3 publications · 80 citations

    3

    h-index

  3. TH
    Taizo Hanai

    Kyushu University, Japan

    2 publications · 120 citations

    2

    h-index

  4. RY
    Rui Yin

    Institute for Bioscience and Biotechnology Research

    2 publications · 153 citations

    2

    h-index

  5. SW
    Shunzhou Wan

    University College London, United Kingdom

    2 publications · 68 citations

    2

    h-index

1–5 of 220

Institutions

111

  1. University of Oxford

    Oxford, United Kingdom

    5 h-index

    10 publications

    426 citations

  2. Jenner Institute

    Oxford, United Kingdom

    4 h-index

    9 publications

    666 citations

  3. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    7 publications

    211 citations

  4. Johns Hopkins University

    Baltimore, United States

    3 h-index

    4 publications

    304 citations

  5. Nagoya University

    Nagoya, Japan

    2 h-index

    7 publications

    570 citations

  6. University of Applied Sciences Utrecht

    Utrecht, Netherlands

    2 h-index

    4 publications

    286 citations

  7. University College London

    London, United Kingdom

    2 h-index

    4 publications

    136 citations

  8. Rice University

    Houston, United States

    2 h-index

    7 publications

    154 citations

1–8 of 111

Venues

  1. Protein Engineering Design and Selection

    PEDS · 3 publications · 356 citations

    3

    h-index

  2. Journal of Theoretical Biology

    3 publications · 99 citations

    3

    h-index

  3. Bioinformatics

    2 publications · 249 citations

    2

    h-index

  4. 2

    h-index

  5. Molecular Immunology

    2 publications · 29 citations

    2

    h-index

1–5