Concepedia

Anchorage Independence

Anchorage Independence is a phenotypic hallmark of neoplastic transformation characterized by the ability of cancer cells to proliferate and form colonies in the absence of adhesion to a solid substrate, distinguishing them from normal cells that require surface attachment for survival and growth.

212

Publications

16.8K

Citations

928

Authors

270

Institutions

Publications per year

2017–2026

14

Variants

Anchorage-independent Growth

Parents

Publications

212

Disruption of epithelial cell-matrix interactions induces apoptosis

SM Frisch, H. Francis · The Journal of Cell Biology · 1994 · 3.3K citations · Full text

, , +17

Overcoming anoikis – pathways to anchorage-independent growth in cancer

Marta C. Guadamillas, Ana Cerezo, Miguel Á. del Pozo · Journal of Cell Science · 2011 · 430 citations

, , +17

Anchorage-independent cell growth signature identifies tumors with metastatic potential

Seiichi Mori, Jean Chang, Eran R. Andrechek et al. · Oncogene · 2009 · 367 citations · Full text

, , +14

T98G: An anchorage‐independent human tumor cell line that exhibits stationary phase G1 arrest in vitro

Gretchen H. Stein · Journal of Cellular Physiology · 1979 · 313 citations

, , +16

Cdc42 Regulates Anchorage-Independent Growth and Is Necessary for Ras Transformation

Rongguo Qiu, Arie Abo, Frank McCormick et al. · Molecular and Cellular Biology · 1997 · 310 citations · Full text

, , +16

1–5 of 212

Authors

928

  1. NH
    Nancy H. Colburn

    National Cancer Institute, United States

    13 publications · 795 citations

    13

    h-index

  2. TD
    Thomas D. Gindhart

    National Cancer Institute, United States

    6 publications · 142 citations

    6

    h-index

  3. YU
    Yoshimasa Uehara

    National Institute of Infectious Diseases, Japan

    4 publications · 293 citations

    4

    h-index

  4. PB
    Paul B. Fisher

    Virginia Commonwealth University, United States

    4 publications · 384 citations

    4

    h-index

  5. HK
    H.P. Klinger

    Albert Einstein College of Medicine, United States

    4 publications · 225 citations

    4

    h-index

1–5 of 928

Institutions

270

  1. Harvard University

    Cambridge, United States

    11 h-index

    28 publications

    1.7K citations

  2. National Cancer Institute

    Bethesda, United States

    11 h-index

    31 publications

    3.4K citations

  3. Columbia University

    New York, United States

    8 h-index

    27 publications

    2.4K citations

  4. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    19 publications

    763 citations

  5. German Cancer Research Center

    Heidelberg, Germany

    4 h-index

    16 publications

    1.9K citations

  6. University of Washington

    Seattle, United States

    4 h-index

    6 publications

    281 citations

  7. University of California, Irvine

    Irvine, United States

    4 h-index

    9 publications

    971 citations

  8. National Institute of Infectious Diseases

    Tokyo, Japan

    4 h-index

    13 publications

    1.4K citations

1–8 of 270

Venues

  1. PubMed

    Repository · 45 publications · 2.1K citations

    25

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.5K citations

    15

    h-index

  3. Molecular and Cellular Biology

    MCB · 13 publications · 985 citations

    13

    h-index

  4. Journal of Virology

    JVI · 12 publications · 819 citations

    12

    h-index

  5. Carcinogenesis

    7 publications · 351 citations

    7

    h-index

1–5