Concepedia

Amplifier Proteins

Amplifier Proteins is a theoretical construct in molecular systems biology that denotes a class of regulatory proteins which enhance signal transduction fidelity and magnitude by selectively increasing the output response of signaling pathways without altering the input stimulus specificity.

18

Publications

2.5K

Citations

98

Authors

46

Institutions

Publications per year

2017–2026

4

Parents

Publications

18

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

Robert Macfarlane · Nature · 1964 · 1.1K citations

, , +16

Solution Structure of BID, an Intracellular Amplifier of Apoptotic Signaling

James J. Chou, Honglin Li, Guy S. Salvesen et al. · Cell · 1999 · 480 citations · Full text

, , +14

Allergy-Associated FcRβ Is a Molecular Amplifier of IgE- and IgG-Mediated In Vivo Responses

David Dombrowicz, Siqi Lin, Véronique Flamand et al. · Immunity · 1998 · 205 citations · Full text

, , +15

Evidence for protein phosphatase inhibitor‐1 playing an amplifier role in β‐adrenergic signaling in cardiac myocytes

Ali El‐Armouche, Thomas Rau, Oliver Zolk et al. · The FASEB Journal · 2003 · 112 citations

, , +15

Transducin: an amplifier protein in vision

Lubert Stryer, James B. Hurley, B K Fung · Trends in Biochemical Sciences · 1981 · 78 citations

, , +12

1–5 of 18

Authors

98

  1. KO
    Keiya Ozawa

    Jichi Medical University, Japan

    3 publications · 76 citations

    3

    h-index

  2. MH
    Mamoru Hasegawa

    ID Pharma (Japan), Japan

    3 publications · 76 citations

    3

    h-index

  3. RX
    Ruifang Xu

    Beijing Friendship Hospital, China

    2 publications · 40 citations

    2

    h-index

  4. LS
    Lubert Stryer

    Stanford University, United States

    2 publications · 154 citations

    2

    h-index

  5. YU
    Yasuji Ueda

    ID Pharma (Japan), Japan

    2 publications · 62 citations

    2

    h-index

1–5 of 98

Institutions

46

  1. Harvard University

    Cambridge, United States

    3 h-index

    11 publications

    3K citations

  2. ID Pharma (Japan)

    Tsukuba, Japan

    3 h-index

    15 publications

    498 citations

  3. Stanford University

    Stanford, United States

    2 h-index

    3 publications

    232 citations

  4. University of Minnesota

    Minneapolis, United States

    2 h-index

    6 publications

    226 citations

  5. Indian Institute of Technology Bombay

    Mumbai, India

    2 h-index

    2 publications

    84 citations

  6. University of Münster

    Münster, Germany

    2 h-index

    5 publications

    392 citations

  7. Japan Science and Technology Agency

    Tokyo, Japan

    2 h-index

    13 publications

    266 citations

  8. University of Groningen

    Groningen, The Netherlands

    2 h-index

    2 publications

    84 citations

1–8 of 46

Venues

  1. PLoS ONE

    2 publications · 84 citations

    2

    h-index

  2. The Journal of Gene Medicine

    2 publications · 40 citations

    2

    h-index

  3. 1

    h-index

  4. The FASEB Journal

    1 publications · 112 citations

    1

    h-index

  5. Cell

    1 publications · 480 citations

    1

    h-index

1–5