Concepedia

Alignment Chaining

Alignment Chaining is a computational method in genome alignment that identifies and concatenates colinear homologous segments across multiple sequences by maximizing a score-based path through a space of pairwise alignment anchors, thereby distinguishing itself from general alignment techniques through its focus on chaining high-scoring local matches under positional and orientation constraints.

13

Publications

614

Citations

44

Authors

25

Institutions

Publications per year

2017–2026

2

Parents

Publications

13

Fast and sensitive multiple alignment of large genomic sequences

Michael Brudno, Michael A. Chapman, Berthold Göttgens et al. · BMC Bioinformatics · 2003 · 199 citations · Full text

, , +10

Chaining algorithms for multiple genome comparison

Mohamed Abouelhoda, Enno Ohlebusch · Journal of Discrete Algorithms · 2004 · 80 citations

, , +11

Fast and sensitive alignment of large genomic sequences

Michael Brudno, Burkhard Morgenstern · 2003 · 64 citations

, , +12

Accurate high throughput alignment via line sweep-based seed processing

Markus Schmidt, Klaus Heese, Arne Kutzner · Nature Communications · 2019 · 51 citations · Full text

, , +10

Chaining multiple-alignment fragments in sub-quadratic time

Gene Myers, Webb Miller · Symposium on Discrete Algorithms · 1995 · 48 citations

, , +9

1–5 of 13

Authors

44

  1. BM
    Burkhard Morgenstern

    University of Göttingen, Germany

    3 publications · 276 citations

    3

    h-index

  2. WM
    Webb Miller

    Pennsylvania State University, United States

    3 publications · 124 citations

    3

    h-index

  3. MB
    Michael Brudno

    University of Toronto, Canada

    2 publications · 263 citations

    2

    h-index

  4. SA
    Svetlana A. Shabalina

    National Center for Biotechnology Information, United States

    1 publications · 10 citations

    1

    h-index

  5. DP
    Dirk Pöhler

    University of Göttingen, Germany

    1 publications · 13 citations

    1

    h-index

1–5 of 44

Institutions

25

  1. Pennsylvania State University

    State College, United States

    3 h-index

    4 publications

    154 citations

  2. National Center for Biotechnology Information

    Bethesda, United States

    2 h-index

    5 publications

    122 citations

  3. Bielefeld University

    Bielefeld, Germany

    2 h-index

    2 publications

    263 citations

  4. Stanford University

    Stanford, United States

    2 h-index

    3 publications

    462 citations

  5. University of Göttingen

    Göttingen, Germany

    2 h-index

    5 publications

    251 citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    1 h-index

    1 publications

    15 citations

  7. University of Arizona

    Tucson, United States

    1 h-index

    1 publications

    48 citations

  8. Laboratoire d'Informatique, de Robotique et de Microélectronique de Montpellier

    Montpellier, France

    1 h-index

    1 publications

    13 citations

1–8 of 25

Venues

  1. Journal of Computational Biology

    2 publications · 45 citations

    2

    h-index

  2. BMC Bioinformatics

    2 publications · 212 citations

    2

    h-index

  3. Bioinformatics

    2 publications · 28 citations

    2

    h-index

  4. Nucleic Acids Research

    1 publications · 13 citations

    1

    h-index

  5. Symposium on Discrete Algorithms

    Conference · 1 publications · 48 citations

    1

    h-index

1–5