Concepedia

Aggregation Thermodynamics

Aggregation Thermodynamics is a theoretical framework that characterizes the energetic drivers and equilibrium states governing the self-assembly of misfolded or partially folded proteins into ordered or disordered aggregates, distinguishing it from general protein folding thermodynamics by focusing specifically on intermolecular interactions, conformational entropy changes, and free energy landscapes associated with aggregate formation.

610

Publications

35.9K

Citations

2.1K

Authors

741

Institutions

Publications per year

2017–2026

113

Parents

Publications

610

Energy Transfer Mechanisms and the Molecular Exciton Model for Molecular Aggregates

Michael Kasha · Radiation Research · 1963 · 1.6K citations

, , +16

Molecular mechanisms of protein aggregation from global fitting of kinetic models

Georg Meisl, Julius B. Kirkegaard, Paolo Arosio et al. · Nature Protocols · 2016 · 789 citations

, , +17

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

Mikio Ohgushi, Akiyoshi Wada · FEBS Letters · 1983 · 728 citations

, , +14

Lineshapes of molecular aggregates, exchange narrowing and intersite correlation

Ernst‐Walter Knapp · Chemical Physics · 1984 · 594 citations

, , +13

Excluded volume as a determinant of macromolecular structure and reactivity

Allen P. Minton · Biopolymers · 1981 · 589 citations

, , +17

1–5 of 610

Authors

2.1K

  1. CJ
    Christopher J. Roberts

    University of Delaware, United States

    10 publications · 608 citations

    10

    h-index

  2. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    8 publications · 1.9K citations

    8

    h-index

  3. JF
    John F. Carpenter

    University of Colorado Boulder, United States

    7 publications · 856 citations

    7

    h-index

  4. TW
    Theodore W. Randolph

    University of Colorado Boulder, United States

    6 publications · 822 citations

    6

    h-index

  5. TN
    Taco Nicolaï

    Le Mans Université, France

    5 publications · 280 citations

    5

    h-index

1–5 of 2.1K

Institutions

741

  1. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    49 publications

    2.2K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    14 h-index

    46 publications

    9.7K citations

  3. University of Delaware

    Newark, United States

    10 h-index

    23 publications

    1.3K citations

  4. Amgen (United States)

    Thousand Oaks, United States

    9 h-index

    47 publications

    5.7K citations

  5. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    32 publications

    1.1K citations

  6. Indian Institute of Science Bangalore

    Bengaluru, India

    8 h-index

    21 publications

    658 citations

  7. Sapienza University of Rome

    Rome, Italy

    8 h-index

    18 publications

    537 citations

  8. Lund University

    Lund, Sweden

    8 h-index

    13 publications

    1.3K citations

1–8 of 741

Venues

  1. The Journal of Physical Chemistry B

    42 publications · 1.7K citations

    22

    h-index

  2. Journal of the American Chemical Society

    JACS · 21 publications · 1.5K citations

    20

    h-index

  3. The Journal of Chemical Physics

    32 publications · 1.3K citations

    19

    h-index

  4. Biophysical Journal

    20 publications · 1.1K citations

    18

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1.8K citations

    13

    h-index

1–5