Concepedia

Adar Enzymes

ADAR Enzymes is a class of RNA-editing enzymes that catalyze the deamination of adenosine to inosine in double-stranded RNA substrates, thereby mediating post-transcriptional gene regulation through site-specific nucleotide modifications.

434

Publications

37.7K

Citations

2.2K

Authors

679

Institutions

Publications per year

2017–2026

168

Variants

Adenosine Deaminases Acting On Rna

Parents

Publications

434

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

Brian Liddicoat, Robert Piskol, Alistair M. Chalk et al. · Science · 2015 · 999 citations · Full text

, , +15

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

Miyoko Higuchi, Stefan Maas, Frank N. Single et al. · Nature · 2000 · 989 citations

, , +14

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

Weidong Yang, Thimmaiah P. Chendrimada, Qingde Wang et al. · Nature Structural & Molecular Biology · 2005 · 771 citations · Full text

, , +14

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

Niamh Mannion, Sam M. Greenwood, Robert S. Young et al. · Cell Reports · 2014 · 682 citations · Full text

, , +14

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

Lily Bazak, Ami Haviv, Michal Barák et al. · Genome Research · 2013 · 664 citations · Full text

, , +14

1–5 of 434

Authors

2.2K

  1. PA
    Peter A. Beal

    University of California, Davis, United States

    27 publications · 1.2K citations

    22

    h-index

  2. BB
    Brenda Bass

    University of Utah, United States

    19 publications · 2.9K citations

    19

    h-index

  3. MA
    Mary A. O’Connell

    Western General Hospital, United Kingdom

    21 publications · 2.4K citations

    18

    h-index

  4. CE
    Charles E. Samuel

    University of California, Santa Barbara, United States

    19 publications · 1.7K citations

    17

    h-index

  5. LP
    Liam P. Keegan

    Western General Hospital, United Kingdom

    17 publications · 2K citations

    16

    h-index

1–5 of 2.2K

Institutions

679

  1. University of Utah

    Salt Lake City, United States

    22 h-index

    66 publications

    9.6K citations

  2. University of California, Davis

    Davis, United States

    20 h-index

    108 publications

    5.8K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    19 h-index

    51 publications

    7.8K citations

  4. Stanford University

    Stanford, United States

    18 h-index

    67 publications

    10.3K citations

  5. Bar-Ilan University

    Ramat Gan, Israel

    18 h-index

    59 publications

    7.5K citations

  6. University of California, Santa Barbara

    Santa Barbara, United States

    17 h-index

    47 publications

    4K citations

  7. Tel Aviv University

    Tel Aviv, Israel

    15 h-index

    36 publications

    6.9K citations

  8. Bambino Gesù Children's Hospital

    Rome, Italy

    14 h-index

    56 publications

    4.8K citations

1–8 of 679

Venues

  1. Nucleic Acids Research

    38 publications · 2.9K citations

    34

    h-index

  2. Journal of Biological Chemistry

    JBC · 26 publications · 3.2K citations

    25

    h-index

  3. RNA

    26 publications · 2K citations

    20

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.7K citations

    14

    h-index

  5. Nature Communications

    13 publications · 1.4K citations

    13

    h-index

1–5