Concepedia

Adaptive Laboratory Evolution

Adaptive Laboratory Evolution is a controlled experimental methodology in which microbial populations are subjected to prolonged selective pressures under defined environmental conditions to drive the emergence of adaptive phenotypes through spontaneous genetic variation and natural selection.

154

Publications

8.1K

Citations

748

Authors

234

Institutions

Publications per year

2017–2026

111

Variants

Ale

Parents

Children

Publications

154

Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium

Ryan A. LaCroix, Troy E. Sandberg, Edward J. O’Brien et al. · Applied and Environmental Microbiology · 2014 · 274 citations · Full text

, , +16

Improving carotenoids production in yeast via adaptive laboratory evolution

Luis H. Reyes, José Manuel Gómez, Katy C. Kao · Metabolic Engineering · 2013 · 215 citations

, , +12

Engineering alcohol tolerance in yeast

Felix H. Lam, Adel Ghaderi, Gerald R. Fink et al. · Science · 2014 · 214 citations · Full text

, , +16

Biosensor-driven adaptive laboratory evolution of l-valine production in Corynebacterium glutamicum

Regina Mahr, Cornelia Gätgens, Jochem Gätgens et al. · Metabolic Engineering · 2015 · 180 citations

, , +16

Adaptive laboratory evolution of a genome-reduced Escherichia coli

Donghui Choe, Jun Hyoung Lee, Minseob Yoo et al. · Nature Communications · 2019 · 174 citations · Full text

, , +17

1–5 of 154

Authors

748

  1. AM
    Adam M. Feist

    University of California San Diego, United States

    23 publications · 1.8K citations

    22

    h-index

  2. BØ
    Bernhard Ø. Palsson

    University of California San Diego, United States

    21 publications · 1.6K citations

    19

    h-index

  3. MJ
    Markus J. Herrgård

    Technical University of Denmark, Denmark

    7 publications · 568 citations

    7

    h-index

  4. RS
    Richard Szubin

    University of California San Diego, United States

    7 publications · 510 citations

    7

    h-index

  5. TE
    Troy E. Sandberg

    Technical University of Denmark, Denmark

    6 publications · 460 citations

    6

    h-index

1–5 of 748

Institutions

234

  1. University of California San Diego

    San Diego, United States

    25 h-index

    127 publications

    9.3K citations

  2. Novo Nordisk Foundation

    Copenhagen, Denmark

    23 h-index

    96 publications

    6.8K citations

  3. Technical University of Denmark

    Kongens Lyngby, Denmark

    22 h-index

    95 publications

    6.8K citations

  4. La Jolla Bioengineering Institute

    San Diego, United States

    8 h-index

    17 publications

    1.1K citations

  5. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    40 publications

    2K citations

  6. Forschungszentrum Jülich

    Jülich, Germany

    6 h-index

    43 publications

    2.4K citations

  7. Chalmers University of Technology

    Gothenburg, Sweden

    5 h-index

    13 publications

    1.1K citations

  8. Texas A&M University

    College Station, United States

    4 h-index

    9 publications

    608 citations

1–8 of 234

Venues

  1. Frontiers in Microbiology

    11 publications · 431 citations

    11

    h-index

  2. Metabolic Engineering

    9 publications · 912 citations

    9

    h-index

  3. Applied and Environmental Microbiology

    AEM · 8 publications · 741 citations

    8

    h-index

  4. Microbial Cell Factories

    8 publications · 254 citations

    8

    h-index

  5. Bioresource Technology

    6 publications · 487 citations

    6

    h-index

1–5