Concepedia

Activity Cliff Analysis Databases

Activity Cliff Analysis Databases is a specialized chemogenomics database that systematically organizes and annotates pairs of structurally similar compounds exhibiting large differences in biological activity to facilitate the identification, analysis, and modeling of activity cliffs in structure–activity relationships.

20

Publications

1K

Citations

48

Authors

25

Institutions

Publications per year

2017–2026

7

Parents

Publications

20

Exploring Activity Cliffs in Medicinal Chemistry

Dagmar Stumpfe, Jürgen Bajorath · Journal of Medicinal Chemistry · 2012 · 365 citations · Full text

, , +14

Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?

Maykel Cruz‐Monteagudo, José L. Medina‐Franco, Yunierkis Pérez‐Castillo et al. · Drug Discovery Today · 2014 · 192 citations

, , +9

Extending the Activity Cliff Concept: Structural Categorization of Activity Cliffs and Systematic Identification of Different Types of Cliffs in the ChEMBL Database

Ye Hu, Jürgen Bajorath · Journal of Chemical Information and Modeling · 2012 · 69 citations

, , +14

Advances in exploring activity cliffs

Dagmar Stumpfe, Huabin Hu, Jürgen Bajorath · Journal of Computer-Aided Molecular Design · 2020 · 63 citations · Full text

, , +16

Molecular Scaffolds with High Propensity to Form Multi-Target Activity Cliffs

Ye Hu, Jürgen Bajorath · Journal of Chemical Information and Modeling · 2010 · 48 citations

, , +17

1–5 of 20

Authors

48

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    13 publications · 723 citations

    11

    h-index

  2. DS
    Dagmar Stumpfe

    University of Bonn, Germany

    5 publications · 483 citations

    5

    h-index

  3. YH
    Ye Hu

    University of Bonn, Germany

    5 publications · 165 citations

    5

    h-index

  4. DD
    Dilyana Dimova

    University of Bonn, Germany

    2 publications · 42 citations

    2

    h-index

  5. NF
    Norbert Furtmann

    University of Bonn, Germany

    2 publications · 37 citations

    2

    h-index

1–5 of 48

Institutions

25

  1. University of Bonn

    Bonn, Germany

    11 h-index

    28 publications

    1.6K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    1 h-index

    1 publications

    31 citations

  3. Translational Genomics Research Institute

    Phoenix, United States

    1 h-index

    1 publications

    11 citations

  4. University of Bari Aldo Moro

    Bari, Italy

    1 h-index

    1 publications

    192 citations

  5. RIKEN Center for Sustainable Resource Science

    Yokohama, Japan

    1 h-index

    1 publications

    10 citations

  6. Hashemite University

    Zarqa, Jordan

    1 h-index

    1 publications

    10 citations

  7. National Center for Biotechnology Information

    Bethesda, United States

    1 h-index

    3 publications

    39 citations

  8. National Institutes of Health

    Bethesda, United States

    1 h-index

    3 publications

    39 citations

1–8 of 25

Venues

  1. Journal of Medicinal Chemistry

    3 publications · 418 citations

    3

    h-index

  2. Journal of Computer-Aided Molecular Design

    3 publications · 84 citations

    3

    h-index

  3. Journal of Chemical Information and Modeling

    JCIM · 2 publications · 117 citations

    2

    h-index

  4. Journal of Cheminformatics

    2 publications · 46 citations

    2

    h-index

  5. Future Medicinal Chemistry

    FMC · 2 publications · 23 citations

    2

    h-index

1–5