Concepedia

Acrab-tolc System

The AcrAB-TolC System is a tripartite bacterial efflux pump complex that functions as a primary mediator of multidrug resistance by actively extruding a broad spectrum of antimicrobial agents from the cell cytoplasm to the external environment.

195

Publications

13.6K

Citations

872

Authors

338

Institutions

Publications per year

2017–2026

71

Variants

Acrab-tolc Efflux Pump

Parents

Publications

195

Properties of AdeABC and AdeIJK Efflux Systems of Acinetobacter baumannii Compared with Those of the AcrAB-TolC System of Escherichia coli

Etsuko Sugawara, Hiroshi Nikaido · Antimicrobial Agents and Chemotherapy · 2014 · 826 citations · Full text

, , +15

<i>Klebsiella pneumoniae</i> AcrAB Efflux Pump Contributes to Antimicrobial Resistance and Virulence

Emma Padilla, Enrique Llobet, Antonio Doménech‐Sánchez et al. · Antimicrobial Agents and Chemotherapy · 2009 · 418 citations · Full text

, , +17

Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli

Joe A. Fralick · Journal of Bacteriology · 1996 · 408 citations · Full text

, , +12

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Thomas Eicher, Hi-jea Cha, Markus A. Seeger et al. · Proceedings of the National Academy of Sciences · 2012 · 343 citations

, , +17

Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors

Gaby Sennhauser, Patrick Amstutz, Christophe Briand et al. · PLoS Biology · 2006 · 326 citations · Full text

, , +17

1–5 of 195

Authors

872

  1. LJ
    Laura J. V. Piddock

    University of Birmingham, United Kingdom

    16 publications · 1.5K citations

    15

    h-index

  2. HI
    Helen I. Zgurskaya

    University of Oklahoma, United States

    13 publications · 1.3K citations

    13

    h-index

  3. MW
    Mark Webber

    University of Birmingham, United Kingdom

    9 publications · 1K citations

    9

    h-index

  4. SB
    Sylvie Baucheron

    Infectiologie et santé publique, France

    7 publications · 485 citations

    7

    h-index

  5. JP
    Jean‐Marie Pagès

    Centre National de la Recherche Scientifique, France

    7 publications · 725 citations

    7

    h-index

1–5 of 872

Institutions

338

  1. University of Birmingham

    Birmingham, United Kingdom

    17 h-index

    66 publications

    5.9K citations

  2. University of Oklahoma

    Norman, United States

    12 h-index

    36 publications

    2.7K citations

  3. The University of Osaka

    Osaka, Japan

    9 h-index

    38 publications

    2.1K citations

  4. Infectiologie et santé publique

    Nouzilly, France

    7 h-index

    24 publications

    1.3K citations

  5. Oak Ridge National Laboratory

    Oak Ridge, United States

    6 h-index

    17 publications

    979 citations

  6. Goethe University Frankfurt

    Frankfurt am Main, Germany

    6 h-index

    26 publications

    3.1K citations

  7. Inserm

    Paris, France

    6 h-index

    30 publications

    2.6K citations

  8. University of California, Berkeley

    Berkeley, United States

    6 h-index

    13 publications

    3.3K citations

1–8 of 338

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 33 publications · 3.7K citations

    28

    h-index

  2. Journal of Antimicrobial Chemotherapy

    JAC · 28 publications · 1.6K citations

    23

    h-index

  3. Journal of Bacteriology

    JB · 16 publications · 1.5K citations

    16

    h-index

  4. Microbial Drug Resistance

    MDR · 6 publications · 313 citations

    6

    h-index

  5. Frontiers in Microbiology

    5 publications · 168 citations

    5

    h-index

1–5