Concepedia

Thomas Eicher

TE

5

Publications

1.3K

Citations

5

H-Index

2006

Active since

Affiliations

University of Zurich(Current)

Goethe University Frankfurt

University of Konstanz

Swiss Integrative Center for Human Health

Thomas Eicher is an author at University of Zurich specializing in biochemistry, natural sciences, and biomolecular engineering.

Top concepts

BiochemistryNatural SciencesMedicineMolecular BiologyStructural BiologyBiomolecular EngineeringChemistryBiophysicsEngineeringDrug Discovery

Publications per year

2006–2014

5

Publications

5

Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism

Markus A. Seeger, A. Schiefner, Thomas Eicher et al. · Science · 2006 · 581 citations

Structural Asymmetry, Biochemistry, Protein Assembly +11

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Thomas Eicher, Hi-jea Cha, Markus A. Seeger et al. · Proceedings of the National Academy of Sciences · 2012 · 339 citations

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB

Thomas Eicher, Markus A. Seeger, Claudio Anselmi et al. · eLife · 2014 · 173 citations · Full text

Proteinlipid Interaction, Molecular Biology, Escherichia Coli +16

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB

Markus A. Seeger, Christoph von Ballmoos, Thomas Eicher et al. · Nature Structural & Molecular Biology · 2008 · 149 citations

Engineered Disulfide Bonds, Biomolecular Engineering, Biochemistry +1

Analysis of AcrB and AcrB/DARPin ligand complexes by LILBID MS

Lorenz Brandstätter, Lucie Sokolová, Thomas Eicher et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2011 · 21 citations

Inorganic Chemistry, Medicinal Chemistry, Acrb/darpin Ligand Complexes +8

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