Bioinformatics

Bioinformatics is an interdisciplinary field that applies computational and statistical methods to the analysis and interpretation of biological data.

103K

Publications

15.5M

Citations

277.5K

Authors

18.3K

Institutions

Publications per year

2017–2026

43K

Parents

ComputingLife Sciences

Children

EpigenomicsGene Expression AnalysisGenome AssemblyGenomicsMetabolomicsMetagenomicsMolecular EvolutionNetwork BiologyPathway AnalysisPhylogenetics

Publications

103K

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin, Ignacio Arganda‐Carreras, Erwin Frise et al. · Nature Methods · 2012 · 70.9K citations

Engineering, Bioinformatics, Biology +9

Trimmomatic: a flexible trimmer for Illumina sequence data

Anthony Bolger, Marc Lohse, Björn Usadel · Bioinformatics · 2014 · 69.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +13

The Sequence Alignment/Map format and SAMtools

Heng Li, Alec Wysoker, Tim Fennell et al. · Bioinformatics · 2009 · 67.5K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

1–5 of 103K

Authors

277.5K

KC
Kuo‐Chen Chou
The Gordon Life Science Institute, United States
185 publications · 32.8K citations
109
h-index
PB
Peer Bork
European Molecular Biology Laboratory, Germany
160 publications · 169.8K citations
104
h-index
DB
David Baker
University of Washington, United States
203 publications · 55.7K citations
104
h-index
YZ
Yang Zhang
University of Michigan, United States
185 publications · 46.2K citations
83
h-index
PF
Paul Flicek
European Bioinformatics Institute, United Kingdom
109 publications · 67.1K citations
81
h-index

1–5 of 277.5K

Institutions

18.3K

1–8 of 18.3K

Venues

Nucleic Acids Research
6.3K publications · 2.7M citations
708
h-index
Bioinformatics
9.6K publications · 2.3M citations
512
h-index
BMC Bioinformatics
4.9K publications · 562.9K citations
258
h-index
Genome biology
1.1K publications · 516.1K citations
234
h-index
Nature Methods
528 publications · 467.8K citations
215
h-index

1–5

See also Bioinformatics
Core Methods	Data Mining Protein Structure Prediction Machine Learning Pattern Recognition Genome-wide Association Studies Hidden Markov Models Support Vector Machines Dynamic Programming Neighbor-joining Multiple Sequence Alignment Gene Prediction Convolutional Neural Networks Random Forests Genome Assembly Naive Bayes K-means Clustering Maximum Likelihood Estimation Markov Chains Protein Structure Alignment Pairwise Alignment Variant Calling Blast Algorithms Phylogenetic Supertree Construction Visualization Long Short-term Memory Networks
Applications	Genomics Proteomics Evolutionary Biology Drug Discovery Precision Medicine Network Biology Pest Control Agriculture Gene Therapy
Data Types	Genomics Proteomics Transcriptomics Metabolic Pathways Gene Regulatory Networks Protein Domains Protein-protein Interaction Networks Protein Structure
Tools	Blast Algorithms Post-implementation Review Workflow Management Systems
Challenges	Large Language Models Bias Reproducibility Studies Multiple Hypothesis Testing Software Validation Distributed Geographic Databases