Hui Yang

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Erwei Zuo, Yidi Sun, Wei Wu et al. · Science · 2019 · 769 citations · Full text

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Haibo Zhou, Jinlin Su, Xinde Hu et al. · Cell · 2020 · 449 citations · Full text

Neurodegenerative Diseases, Neuroregeneration, Medicine +12

Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing

Huashui Ai, Xiaodong Fang, Bin Yang et al. · Nature Genetics · 2015 · 401 citations

Biology, Whole-genome Sequencing, Comparative Genomics +11

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Chunlong Xu, Yingsi Zhou, Qingquan Xiao et al. · Nature Methods · 2021 · 340 citations · Full text

Engineering, Programmable Rna, Rna Biology +9

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Haibo Zhou, Junlai Liu, Changyang Zhou et al. · Nature Neuroscience · 2018 · 274 citations

Transcriptional Regulation, Systems Biology, In Vivo Gene Therapy +12