Tanglong Yuan

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Erwei Zuo, Yidi Sun, Wei Wu et al. · Science · 2019 · 769 citations · Full text

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Chunlong Xu, Yingsi Zhou, Qingquan Xiao et al. · Nature Methods · 2021 · 340 citations · Full text

Engineering, Programmable Rna, Rna Biology +9

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Erwei Zuo, Yidi Sun, Tanglong Yuan et al. · Nature Methods · 2020 · 168 citations

Engineering, Genome Surgery, Natural Sciences +12

Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

Sangsin Lee, Ning Ding, Yidi Sun et al. · Science Advances · 2020 · 80 citations · Full text

PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function

Ying Chen, Hai-Sheng Zhang, Guo‐Hua Fong et al. · Journal of Biological Chemistry · 2015 · 65 citations · Full text

Chronic Inflammatory Diseases, Protein Secretion, Gastrointestinal Pharmacology +20