Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients

Elena Khanova, Raymond Wu, Wen Wang, +14

Hepatology

Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth

Xue Li, Lingmei Kong, Qihong Yang, +6

Journal of Biological Chemistry

Signaling PathwayBiochemistryMedicineEnzyme Activity AssaysColorectal Cancer +13

Resveratrol prevents hyperglycemia-induced endothelial dysfunction via activation of adenosine monophosphate-activated protein kinase

Qiang Xu, Xinzhong Hao, Qihong Yang, +1

Biochemical and Biophysical Research Communications

Metabolic SyndromeInsulin SignalingHyperglycemia-induced Endothelial DysfunctionBiochemistryMedicine +10

A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population

Hu-Lin Wang, Qiang Xu, Zhang Wang, +5

Clinica Chimica Acta

HypertensionGenetic DeterminantChinese Han PopulationGeneticsPhysiology +7

Protective effect of tetramethylpyrazine isolated from Ligusticum chuanxiong on nephropathy in rats with streptozotocin-induced diabetes

Qihong Yang, Yong Liang, Xu Qiang, +3

Phytomedicine

MedicineDiabetesChronic Kidney DiseaseDiabetic Kidney DiseaseStreptozotocin-induced Diabetes +5

Induction of autophagy and apoptosis by miR-148a through the sonic hedgehog signaling pathway in hepatic stellate cells.

Xu-You Liu, Ya-jun He, Qihong Yang, +5

PubMed

Hepatic Stellate CellsApoptosisCell DeathPathologyEpigenetics +20

Antimicrobial Peptide Brevinin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells

Xiaoman Ju, Dongmei Fan, Lingmei Kong, +5

Molecules

USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide

Shaohua Zhang, Xiaoman Ju, Qihong Yang, +5

Biochemical and Biophysical Research Communications

Tumor BiologyMedicineColorectal CancerPathologyCell Death +6

Resveratrol ameliorates high glucose-induced oxidative stress injury in human umbilical vein endothelial cells by activating AMPK

Dayan Zhou, Yong Su, Pan Gao, +3

Life Sciences

InflammationAtherosclerosisMedicineDiabetesPhysiology +9

Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras

Kinji Asahina, Steven Balog, Edward Hwang, +10

American Journal of Physiology-Gastrointestinal and Liver Physiology