Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li, +36

Cancer Cell

Immune EvasionMedicineStem Cell MobilizationImmunologyStem Cell Research +6

Rethinking Classification and Localization for Object Detection

Yue Wu, Yinpeng Chen, Lu Yuan, +4

Convolutional Neural NetworkObject CategorizationMachine LearningConvolution HeadEngineering +14

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Hengyou Weng, Feng Huang, Zhaojin Yu, +31

Cancer Cell

Hematological MalignancyGlutamine MetabolismMedicineAcute Myeloid LeukemiaMixed-phenotype Acute Leukemia +6

CtIP Maintains Stability at Common Fragile Sites and Inverted Repeats by End Resection-Independent Endonuclease Activity

Hailong Wang, Yongjiang Li, Lan N. Truong, +12

Molecular Cell

Genome InstabilityNatural SciencesEndocytic PathwayMolecular BiologyDna Replication +7

Mutations in DNA2 Link Progressive Myopathy to Mitochondrial DNA Instability

Dario Ronchi, Alessio Di Fonzo, Weiqiang Lin, +19

The American Journal of Human Genetics

Mitochondrial MyopathyGenome InstabilityMendelian DisorderMitochondrial BiogenesisMitochondrial Function +12

Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells

Jiawei Zhang, Yichao Gan, Hongzhi Li, +18

Nature Communications

A Privacy-Preserving Charging Scheme for Electric Vehicles Using Blockchain and Fog Computing

Hongzhi Li, Dezhi Han, Mingdong Tang

IEEE Systems Journal

EngineeringFog Computing SecurityInformation SecurityDistributed FcnsElectric Vehicles +14

CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine

Ying Gu, Ting Chen, Zhipeng Meng, +15

Blood

Simulated scaling method for localized enhanced sampling and simultaneous “alchemical” free energy simulations: A general method for molecular mechanical, quantum mechanical, and quantum mechanical/molecular mechanical simulations

Hongzhi Li, Mikolai Fajer, Wei Yang

The Journal of Chemical Physics

METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation

Meilin Xue, Lei Dong, Honghai Zhang, +32

Journal of Hematology & Oncology