Christopher F. Stratton

Cheminformatic comparison of approved drugs from natural product versus synthetic origins

Christopher F. Stratton, David Newman, Derek S. Tan · Bioorganic & Medicinal Chemistry Letters · 2015 · 188 citations

Medicinal Chemistry, Cheminformatic Comparison, Bioequivalence +7

A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion

Felix Kopp, Christopher F. Stratton, Lakshmi B. Akella et al. · Nature Chemical Biology · 2012 · 154 citations · Full text

Combinatorial Chemistry, Novel Organocatalysts, Diversity Oriented Synthesis +10

Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli

Salma Rafi, Polina Novichenok, S. Kolappan et al. · Journal of Biological Chemistry · 2006 · 112 citations · Full text

Mechanism and Inhibition of saFabI, the Enoyl Reductase from<i>Staphylococcus aureus</i>

Hua Xu, Todd J. Sullivan, Jun‐ichiro Sekiguchi et al. · Biochemistry · 2008 · 65 citations · Full text

Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-Name Drugs, Natural Product-Like Libraries, and Drug-Like Libraries

Todd A. Wenderski, Christopher F. Stratton, Renato A. Bauer et al. · Methods in molecular biology · 2014 · 61 citations · Full text

Targeted Library, Library Design, Data Science +10