Derek S. Tan

Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis

Julián A. Ferreras, Jae‐Sang Ryu, Federico A. Di Lello et al. · Nature Chemical Biology · 2005 · 289 citations · Full text

Biosynthesis, Biochemistry, Mycobacterium Tuberculosis +9

Active site remodelling accompanies thioester bond formation in the SUMO E1

Shaun K. Olsen, Allan D. Capili, Xuequan Lu et al. · Nature · 2010 · 203 citations · Full text

Biochemistry, Protein Assembly, Protein Folding +8

Cheminformatic comparison of approved drugs from natural product versus synthetic origins

Christopher F. Stratton, David Newman, Derek S. Tan · Bioorganic & Medicinal Chemistry Letters · 2015 · 188 citations

Medicinal Chemistry, Cheminformatic Comparison, Bioequivalence +7

Stereoselective Synthesis of over Two Million Compounds Having Structural Features Both Reminiscent of Natural Products and Compatible with Miniaturized Cell-Based Assays

Derek S. Tan, Michael A. Foley, Matthew D. Shair et al. · Journal of the American Chemical Society · 1998 · 181 citations

Combinatorial Chemistry, Bioorganic Chemistry, Engineering +18

Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion

Renato A. Bauer, Todd A. Wenderski, Derek S. Tan · Nature Chemical Biology · 2012 · 164 citations · Full text

Diversity Oriented Synthesis, Alkene Metathesis, Natural Sciences +5