Hiroyuki Shibata

Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

Shunsuke Kato, Shuang-Yin Han, Wen Liu et al. · Proceedings of the National Academy of Sciences · 2003 · 869 citations · Full text

Engineering, Molecular Biology, Function–mutation Relationships +17

Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the <i>Apc</i> Gene

Hiroyuki Shibata, Kaoru Toyama, Hisashi Shioya et al. · Science · 1997 · 613 citations

Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer

Hisatsugu Ohori, Hiroyuki Yamakoshi, Masaki Tomizawa et al. · Molecular Cancer Therapeutics · 2006 · 242 citations · Full text

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

Masashi Kanai, Yoshihiko Otsuka, Kazunori Otsuka et al. · Cancer Chemotherapy and Pharmacology · 2013 · 186 citations

Pharmaceutical Science, Oncology, Medicine +7

Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030

Liu Y, Haoyang Li, Pui‐Kai Li et al. · British Journal of Cancer · 2011 · 165 citations · Full text