Kazunori Otsuka

Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

Shunsuke Kato, Shuang-Yin Han, Wen Liu et al. · Proceedings of the National Academy of Sciences · 2003 · 869 citations · Full text

Engineering, Molecular Biology, Function–mutation Relationships +17

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

Masashi Kanai, Yoshihiko Otsuka, Kazunori Otsuka et al. · Cancer Chemotherapy and Pharmacology · 2013 · 186 citations

Pharmaceutical Science, Oncology, Medicine +7

The relationship among p53 oligomer formation, structure and transcriptional activity using a comprehensive missense mutation library

Tomohiro Kawaguchi, Shunsuke Kato, Kazunori Otsuka et al. · Oncogene · 2005 · 106 citations

Somatic Variant, Natural Sciences, Genetics +7

Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

Kazuko Shiraishi, Shunsuke Kato, Shuang-Yin Han et al. · Journal of Biological Chemistry · 2003 · 94 citations · Full text

Engineering, Genetics, Molecular Biology +17

Lack of Correlation between p53-Dependent Transcriptional Activity and the Ability to Induce Apoptosis among 179 Mutant p53s

Yuichi Kakudo, Hiroyuki Shibata, Kazunori Otsuka et al. · Cancer Research · 2005 · 89 citations · Full text

P53-dependent Apoptosis, Apoptosis, Cell Death +16