Hirotaka Mizuno

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

Markus Hoffmann, Heike Hofmann-Winkler, Joan C. Smith et al. · EBioMedicine · 2021 · 398 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

Jill Chrencik, C. Roth, Masahiko Terakado et al. · Cell · 2015 · 213 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Evaluations of the Selectivities of the Diacylglycerol Kinase Inhibitors R59022 and R59949 Among Diacylglycerol Kinase Isozymes Using a New Non-Radioactive Assay Method

Mayu Sato, Ke Liu, Saori Sasaki et al. · Pharmacology · 2013 · 94 citations

Life Sciences, Biochemistry, Pharmacology +16

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

Markus Hoffmann, Heike Hofmann-Winkler, Joan C. Smith et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 80 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation In Vivo and Regulates Urethral Tension

Hiroshi Saga, Akira Ohhata, Akio Hayashi et al. · PLoS ONE · 2014 · 57 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13