Heike Hofmann-Winkler

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

Markus Hoffmann, Prerna Arora, Rüdiger Groß et al. · Cell · 2021 · 1K citations · Full text

Pharmacy, Immunology, Infectious Diseases +12

TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

Adeline Heurich, Heike Hofmann-Winkler, Stefanie Gierer et al. · Journal of Virology · 2013 · 935 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

Markus Hoffmann, Kirstin Mösbauer, Heike Hofmann-Winkler et al. · Nature · 2020 · 509 citations · Full text

Medicine, Infectious Diseases, Pharmacology +10

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

Markus Hoffmann, Heike Hofmann-Winkler, Joan C. Smith et al. · EBioMedicine · 2021 · 398 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium

Stephanie Bertram, Ronald Dijkman, Matthias Habjan et al. · Journal of Virology · 2013 · 376 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17