Kim T. Tran

A homeostatic model of IκB metabolism to control constitutive NF‐κB activity

Ellen L O'Dea, Derren Barken, Raechel Peralta et al. · Molecular Systems Biology · 2007 · 134 citations · Full text

Constitutive Nf‐κb Activity, Immune Regulation, Immunology +17

Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1–Nuclear Factor Erythroid 2-Related Factor 2 (Keap1–Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases

Jakob S. Pallesen, Kim T. Tran, Anders Bach · Journal of Medicinal Chemistry · 2018 · 107 citations · Full text

Lipid Peroxidation, Their Potential, Antioxidant Enzymes +20

A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

Kim T. Tran, Jakob S. Pallesen, Sara M. Ø. Solbak et al. · Journal of Medicinal Chemistry · 2019 · 95 citations · Full text

Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

Jakob S. Pallesen, Dilip Narayanan, Kim T. Tran et al. · Journal of Medicinal Chemistry · 2021 · 54 citations · Full text

Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

Dilip Narayanan, Kim T. Tran, Jakob S. Pallesen et al. · Journal of Medicinal Chemistry · 2022 · 39 citations · Full text