Sara M. Ø. Solbak

A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

Kim T. Tran, Jakob S. Pallesen, Sara M. Ø. Solbak et al. · Journal of Medicinal Chemistry · 2019 · 99 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The dynamics of linear polyubiquitin

Alexander Jussupow, Ana C. Messias, Ralf Stehle et al. · Science Advances · 2020 · 63 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

Jakob S. Pallesen, Dilip Narayanan, Kim T. Tran et al. · Journal of Medicinal Chemistry · 2021 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

Ulrike Leurs, Anders B. Klein, Ethan D. McSpadden et al. · Proceedings of the National Academy of Sciences · 2021 · 52 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

Dilip Narayanan, Kim T. Tran, Jakob S. Pallesen et al. · Journal of Medicinal Chemistry · 2022 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17