Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation

Yu-Wen Zhang, Yanli Su, Olga V. Volpert, +1

Proceedings of the National Academy of Sciences

Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Mark Merchant, Xiaolei Ma, Henry R. Maun, +26

Proceedings of the National Academy of Sciences

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models

Brian Cao, Yanli Su, Marianne Oskarsson, +5

Proceedings of the National Academy of Sciences

Antitumor ActivityImmunologyGrowth Factor/scatter FactorCancer BiologyGlioma +17

Proliferation and invasion: Plasticity in tumor cells

Chong Gao, Qian Xie, Yanli Su, +7

Proceedings of the National Academy of Sciences

Biological MicroenvironmentsPathologyTumor CellsCell ProliferationGlioma +14

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Kyle Furge, Julie Koeman, Karl Dykema, +5

Proceedings of the National Academy of Sciences

GeneticsEpigeneticsTumor BiologyTumor HeterogeneityChromosome Transcriptome +14

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Qian Xie, Robert H. Bradley, Liang Kang, +14

Proceedings of the National Academy of Sciences

GliomaTumor BiologyNeuro-oncologyHgf Paracrine EnvironmentHepatocyte Growth Factor +15

Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer

Carrie R. Graveel, Jack D. DeGroot, Yanli Su, +12

Proceedings of the National Academy of Sciences

Breast OncologyOncologyMammary CarcinomasAggressive Breast CancersMedicine +13

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele

Carrie Graveel, Yanli Su, Julie Koeman, +7

Proceedings of the National Academy of Sciences

Targeted disruption of <i>Mig-6</i> in the mouse genome leads to early onset degenerative joint disease

Yu-Wen Zhang, Yanli Su, Nathan Lanning, +5

Proceedings of the National Academy of Sciences

MET Kinase Inhibitor SGX523 Synergizes with Epidermal Growth Factor Receptor Inhibitor Erlotinib in a Hepatocyte Growth Factor–Dependent Fashion to Suppress Carcinoma Growth

Yuwen Zhang, Ben Staal, Curt J. Essenburg, +7

Cancer Research