Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers

Mingxia Gu, Ning‐Yi Shao, Silin Sa, +18

Cell stem cell

O-linked β- <i>N</i> -acetylglucosamine transferase is indispensable in the failing heart

Lewis J. Watson, Heberty Tarso Facundo, Gladys A. Ngoh, +7

Proceedings of the National Academy of Sciences

Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease

Mohamed Ameen, Laksshman Sundaram, Mengcheng Shen, +16

Cell

CardiomyopathyDevelopmental BiologyCardiac ReprogrammingMorphogenesisCongenital Heart Defect +7

Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity

Silin Sa, Mingxia Gu, James Chappell, +14

American Journal of Respiratory and Critical Care Medicine

Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells

Syed J. Khundmiri, Melissa A. Metzler, Mohamed Ameen, +3

American Journal of Physiology-Cell Physiology

Statins improve endothelial function via suppression of epigenetic-driven EndMT

Chun Liu, Mengcheng Shen, Wilson Lek Wen Tan, +13

Nature Cardiovascular Research

InflammationCell SignalingEndothelial DysfunctionVascular BiologyEpigenetic-driven Endmt +3

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy

Isaac Perea‐Gil, Timon Seeger, Arne A.N. Bruyneel, +19

European Heart Journal

Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates

Kitchener D. Wilson, Mohamed Ameen, Hongchao Guo, +16

Developmental Cell

Viral ReplicationCardiac ReprogrammingHuman RetrovirusImmunologyVirology +6

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods

Jared M. Churko, Jaecheol Lee, Mohamed Ameen, +10

Nature Biomedical Engineering

Induced Pluripotent Stem CellEpigenomic DifferencesGeneticsInduced Pluripotent Stem CellsMedicine +8

Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathway

Syed J. Khundmiri, Vishal Amin, J. B. Henson, +4

American Journal of Physiology-Cell Physiology