James Chappell

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers

Mingxia Gu, Ning‐Yi Shao, Silin Sa et al. · Cell stem cell · 2016 · 208 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Cellular senescence impairs the reversibility of pulmonary arterial hypertension

Diederik E. van der Feen, Guido P. L. Bossers, Quint A. J. Hagdorn et al. · Science Translational Medicine · 2020 · 141 citations · Full text

Education, Cardiology, Physiology +14

Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity

Silin Sa, Mingxia Gu, James Chappell et al. · American Journal of Respiratory and Critical Care Medicine · 2016 · 94 citations · Full text

Life Sciences, Cardiology, Molecular Medicine +17

PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension

Jan K. Hennigs, Aiqin Cao, Caiyun G. Li et al. · Circulation Research · 2020 · 86 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation

Daniel Seung Kim, Viviana I. Risca, David L. Reynolds et al. · Nature Genetics · 2021 · 82 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +14