Ekaterine Chighladze

Author

Johns Hopkins Medicine

Also Known As

E Chighladze, Ekaterine Chighladze

Publications

606

Citations

H-Index

Concepts

All Affiliations

Johns Hopkins Medicine Johns Hopkins University Institute of Neurobiology CHDI Foundation University of Baltimore

About

Ekaterine Chighladze is an author at Johns Hopkins Medicine specializing in molecular biology, medicine, and systems biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	355
2	Molecular Biology	5	5	355
3	Natural Sciences	4	4	323
4	Cell Biology	4	4	285
5	Biochemistry	1	1	135

Ekaterine Chighladze

Publications

606

Citations

H-Index

Page 1

	Year	Citations
Mutant Huntingtin N-terminal Fragments of Specific Size Mediate Aggregation and Toxicity in Neuronal Cells Tamara Ratovitski, Marjan Guček, Haibing Jiang, Journal of Biological Chemistry	2009	139
Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis Tamara Ratovitski, Ekaterine Chighladze, Nicolas Arbez, Cell Cycle Huntingtin Protein InteractionsMitochondrial DysfunctionMolecular BiologyQuantitative Proteomic AnalysisProtein Folding	2012	135
PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD) Tamara Ratovitski, Nicolas Arbez, Jacqueline C. Stewart, Cell Cycle Epigenetic ChangeGeneticsGenomic MechanismMolecular BiologyDisease Gene Identification	2015	70
N-Terminal Proteolysis of Full-Length Mutant Huntingtin in an Inducible PC12 Cell Model of Huntington’s Disease Tamara Ratovitski, Masayuki Nakamura, James D'Ambola, Cell Cycle	2007	61
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats Tamara Ratovitski, Robert N. O’Meally, Mali Jiang, Journal of Proteome Research Biological Mass SpectrometryMolecular BiologyMost PtmsProteomic TechnologyProtein Expression	2017	60
Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity Nicolas Arbez, Tamara Ratovitski, Elaine Roby, Journal of Biological Chemistry Several PtmsMitophagyProtein FunctionProtein ExpressionMitochondrial Function	2017	58
Cysteine Proteases Bleomycin Hydrolase and Cathepsin Z Mediate N-terminal Proteolysis and Toxicity of Mutant Huntingtin Tamara Ratovitski, Ekaterine Chighladze, Elaine Waldron, Journal of Biological Chemistry	2011	51
Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity Tamara Ratovitski, Mali Jiang, Robert N. O’Meally, Human Molecular Genetics Epigenetic ChangeNeurotransmitterMolecular BiologyHtt SolubilityPhase Transition Behavior	2021	32

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