Minimum Information about a Biosynthetic Gene cluster

Marnix H. Medema, Renzo Kottmann, Pelin Yilmaz, +151

Nature Chemical Biology

Structure and Biosynthesis of Heat-Stable Antifungal Factor (HSAF), a Broad-Spectrum Antimycotic with a Novel Mode of Action

Fengan Yu, Kathia Zaleta-Rivera, Xiangcheng Zhu, +6

Antimicrobial Agents and Chemotherapy

Meta-omic Characterization of the Marine Invertebrate Microbial Consortium That Produces the Chemotherapeutic Natural Product ET-743

Christopher M. Rath, Benjamin Janto, Josh Earl, +13

ACS Chemical Biology

EngineeringTunicate Ecteinascidia TurbinataMolecular BiologyBiosynthesisMicrobial Ecology +14

Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

Sung Ryeol Park, Ashootosh Tripathi, Jianfeng Wu, +9

Nature Communications

Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C—H Functionalization

Andrew N. Lowell, Matthew D. DeMars, Samuel T. Slocum, +9

Journal of the American Chemical Society

Bioorganic ChemistryEngineeringTerminal Pks ModulesOxidation State AdjustmentsMolecular Biology +19

Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels–Alderase

Qingyun Dan, Sean A. Newmister, Kimberly R. Klas, +15

Nature Chemistry

BiologyBiosynthesisBiochemistryFungal Cell BiologyNatural Sciences +2

Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase

Vikram V. Shende, Yogan Khatri, Sean A. Newmister, +8

Journal of the American Chemical Society

A Bidomain Nonribosomal Peptide Synthetase Encoded by <i>FUM14</i> Catalyzes the Formation of Tricarballylic Esters in the Biosynthesis of Fumonisins

Kathia Zaleta-Rivera, Chunping Xu, Fengan Yu, +6

Biochemistry

Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C–C Bond-Forming Cascade

Shasha Li, Andrew N. Lowell, Fengan Yu, +6

Journal of the American Chemical Society

EngineeringMolecular BiologyC–c Bond-forming CascadeChemical BiologyBioactive Indole Alkaloids +14

Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(−)-notoamide, paraherquamide and malbrancheamide pathways

Shengying Li, Krithika Srinivasan, Hong Tran, +7

MedChemComm