Matthew D. DeMars

Controlled Oxidation of Remote sp³ C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity

Kaidong Zhang, Brian M. Shafer, Matthew D. DeMars et al. · Journal of the American Chemical Society · 2012 · 202 citations

Engineering, Biochemistry, Medicinal Chemistry +17

Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C—H Functionalization

Andrew N. Lowell, Matthew D. DeMars, Samuel T. Slocum et al. · Journal of the American Chemical Society · 2017 · 93 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis

Jia-Hui Tay, Alonso J. Argüelles, Matthew D. DeMars et al. · Journal of the American Chemical Society · 2017 · 79 citations · Full text

Pharmacy, Biochemistry, Chemistry +11

Recycling Upstream Redox Enzymes Expands the Regioselectivity of Cycloaddition in Pseudo-Aspidosperma Alkaloid Biosynthesis

Mohamed O. Kamileen, Matthew D. DeMars, Benke Hong et al. · Journal of the American Chemical Society · 2022 · 30 citations · Full text

Pharmacy, Biochemistry, Chemical Biology +15

Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics

Song Yang, Matthew D. DeMars, Jessica M. Grandner et al. · Journal of the American Chemical Society · 2020 · 28 citations · Full text

Life Sciences, Biochemistry, Chemistry +17