Andrew N. Lowell

Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C—H Functionalization

Andrew N. Lowell, Matthew D. DeMars, Samuel T. Slocum et al. · Journal of the American Chemical Society · 2017 · 90 citations · Full text

Bioorganic Chemistry, Engineering, Terminal Pks Modules +21

Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C–C Bond-Forming Cascade

Shasha Li, Andrew N. Lowell, Fengan Yu et al. · Journal of the American Chemical Society · 2015 · 76 citations

Engineering, Molecular Biology, C–c Bond-forming Cascade +16

Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering

Irina Koryakina, Christian Kasey, John B. McArthur et al. · ACS Chemical Biology · 2016 · 68 citations · Full text

Engineering, Combinatorial Biosynthesis, Molecular Biology +21

Engineering the Substrate Specificity of a Modular Polyketide Synthase for Installation of Consecutive Non-Natural Extender Units

Edward Kalkreuter, Jared Matthew CroweTipton, Andrew N. Lowell et al. · Journal of the American Chemical Society · 2019 · 53 citations

Bioorganic Chemistry, Engineering, Molecular Biology +20

A Concise Synthesis of the Naphthalene Portion of Purpuromycin

Andrew N. Lowell, Michael W. Fennie, Marisa C. Kozlowski · The Journal of Organic Chemistry · 2008 · 50 citations

Engineering, Stobbe Condensation, Organic Chemistry +9