Activation of Akt and eIF4E Survival Pathways by Rapamycin-Mediated Mammalian Target of Rapamycin Inhibition

Shi-Yong Sun, Laura M. Rosenberg, Xuerong Wang, +4

Cancer Research

Testosterone Relaxes Rabbit Coronary Arteries and Aorta

Ping Yue, Kanu Chatterjee, Carolyn M. Beale, +2

Circulation

Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.

Shi‐Yong Sun, Ping Yue, Marcia I. Dawson, +9

PubMed

Cell ProliferationCancer BiologyTumor BiologyDifferential EffectsCancer Cell Biology +14

p53 Upregulates Death Receptor 4 Expression through an Intronic p53 Binding Site

Ping Yue, Fadlo R. Khuri, Shi‐Yong Sun

Cancer Research

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment

Puyu Shi, You-Take Oh, Guojing Zhang, +10

Cancer Letters

Lung Cancer TreatmentSystems BiologyOncogenic AgentMedicineProtein Hyperactivation +7

c-Jun NH2-Terminal Kinase-Mediated Up-regulation of Death Receptor 5 Contributes to Induction of Apoptosis by the Novel Synthetic Triterpenoid Methyl-2-Cyano-3,12-Dioxooleana-1, 9-Dien-28-Oate in Human Lung Cancer Cells

Wei Zou, Ping Yue, Zhongmei Zhou, +4

Cancer Research

The Proteasome Inhibitor PS-341 (Bortezomib) Up-Regulates DR5 Expression Leading to Induction of Apoptosis and Enhancement of TRAIL-Induced Apoptosis Despite Up-Regulation of c-FLIP and Survivin Expression in Human NSCLC Cells

Ping Yue, Shuzhen Chen, Liping Hu, +3

Cancer Research

Enhancing Mammalian Target of Rapamycin (mTOR)–Targeted Cancer Therapy by Preventing mTOR/Raptor Inhibition-Initiated, mTOR/Rictor-Independent Akt Activation

Xuerong Wang, Ping Yue, Young Ae Kim, +3

Cancer Research

Cancer TherapyCancer BiologyTumor BiologyMammalian TargetReceptor Tyrosine Kinase +15

Inhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation

Xuerong Wang, Ping Yue, Chi-Bun Chan, +7

Molecular and Cellular Biology

Mtor-targeted Cancer TherapyMammalian TargetSignal TransductionMtor InhibitorsSignaling Pathway +12

Perifosine Inhibits Mammalian Target of Rapamycin Signaling through Facilitating Degradation of Major Components in the mTOR Axis and Induces Autophagy

Lei Fu, Young‐Ae Kim, Xuerong Wang, +5

Cancer Research

MitophagyMtor AxisChemoprevention StrategyClassic Mtor InhibitorsImmunology +21