You-Take Oh

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment

Puyu Shi, You-Take Oh, Guojing Zhang et al. · Cancer Letters · 2016 · 181 citations

Lung Cancer Treatment, Systems Biology, Oncogenic Agent +9

Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation

Puyu Shi, You-Take Oh, Liang Deng et al. · Clinical Cancer Research · 2017 · 140 citations · Full text

ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1

You-Take Oh, Ping Yue, Sumin Kang et al. · Journal of Biological Chemistry · 2010 · 68 citations · Full text

Dr5 Promoter Activity, Erk/ribosomal S6 Kinase, Signal Transduction +13

Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling

You-Take Oh, Ping Yue, Dongsheng Wang et al. · Oncotarget · 2015 · 49 citations · Full text

The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5

Bo Han, Weilong Yao, You-Take Oh et al. · Oncotarget · 2015 · 42 citations · Full text