Activation of Akt and eIF4E Survival Pathways by Rapamycin-Mediated Mammalian Target of Rapamycin Inhibition

Shi-Yong Sun, Laura M. Rosenberg, Xuerong Wang, +4

Cancer Research

Inhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation

Xuerong Wang, Ping Yue, Chi-Bun Chan, +7

Molecular and Cellular Biology

Mtor-targeted Cancer TherapyMammalian TargetSignal TransductionMtor InhibitorsSignaling Pathway +12

Overexpression of Bcl2 Blocks TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis in Human Lung Cancer Cells

Shi-Yong Sun, Ping Yue, Jun-Ying Zhou, +4

Biochemical and Biophysical Research Communications

ApoptosisImmunologyCell DeathImmune Checkpoint InhibitorTumor Suppressor +5

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

Shi-Yong Sun, Ping Yue, Gen Sheng Wu, +4

Oncogene

OncologyOncogenic AgentMedicineApoptosisSynthetic Retinoid Cd437 +10

Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer

Taofeek K. Owonikoko, Guojing Zhang, Hyun S. Kim, +13

Journal of Translational Medicine

Human BRE1 Is an E3 Ubiquitin Ligase for Ebp1 Tumor Suppressor

Zhixue Liu, Sang-Muk Oh, Masashi Okada, +8

Molecular Biology of the Cell

Transcriptional RegulationSystems BiologyOncologyE3 Ubiquitin LigaseCell Regulation +13

The Combination of RAD001 and NVP-BEZ235 Exerts Synergistic Anticancer Activity against Non-Small Cell Lung Cancer In Vitro and In Vivo

Cheng‐Xiong Xu, Yikun Li, Ping Yue, +4

PLoS ONE

ImmunologyMtor Allosteric InhibitorCancer BiologyTumor BiologyMtor-targeted Caner Therapy +14

Therapeutic Potential and Molecular Mechanism of a Novel, Potent, Nonpeptide, Smac Mimetic SM-164 in Combination with TRAIL for Cancer Treatment

Jianfeng Lü, Donna McEachern, Haiying Sun, +12

Molecular Cancer Therapeutics

Therapeutic PotentialCancer BiologySmac MimeticsTumor BiologyMolecular Pharmacology +14

Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells

Yidan Lin, Ping Yue, Doris M. Benbrook, +3

Molecular Cancer Therapeutics

CAAT/Enhancer Binding Protein Homologous Protein–Dependent Death Receptor 5 Induction Is a Major Component of SHetA2-Induced Apoptosis in Lung Cancer Cells

Yi-Dan Lin, Shuzhen Chen, Ping Yue, +7

Cancer Research