David A. Egan

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs, Joep de Ligt, Oded Kopper et al. · Cell · 2017 · 1.9K citations · Full text

Breast Oncology, Oncology, Engineering +11

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

Qihong Huang, Kiranmai Gumireddy, Mariëtte Schrier et al. · Nature Cell Biology · 2008 · 962 citations

Oncology, Medicine, Microrna Detection +7

Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation

Carlos le Sage, Remco Nagel, David A. Egan et al. · The EMBO Journal · 2007 · 803 citations · Full text

Intra-tumour diversification in colorectal cancer at the single-cell level

Sophie Roerink, Nobuo Sasaki, Henry Lee-Six et al. · Nature · 2018 · 554 citations

Tumor Biology, Tumor Heterogeneity, Medicine +5

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1

Coenraad Kuijl, Nigel D. L. Savage, Marije Marsman et al. · Nature · 2007 · 297 citations · Full text

Prokaryotic System, Signal Transduction, Intracellular Bacterial Growth +11