Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group

William Kemnitzer, John Drewe, Songchun Jiang, +18

Journal of Medicinal Chemistry

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions

William Kemnitzer, Shailaja Kasibhatla, Songchun Jiang, +17

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +9

Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

Dirksen E. Bussiere, Lili Xie, Honnappa Srinivas, +24

Nature Chemical Biology

Signal TransductionMolecular ResearchMolecular RegulationMedicineNatural Sciences +8

A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid

Shailaja Kasibhatla, Katayoun A. Jessen, Sergei Maliartchouk, +13

Proceedings of the National Academy of Sciences

Chemoprevention StrategyApoptosisImmunologyCell DeathPharmacotherapy +16

Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of <i>N</i>-Alkyl Substituted Pyrrole Fused at the 7,8-Positions

William Kemnitzer, John Drewe, Songchun Jiang, +11

Journal of Medicinal Chemistry

Chemoprevention StrategyApoptosisCell DeathNew SeriesHeterocycle Chemistry +15

Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions

William Kemnitzer, John Drewe, Songchun Jiang, +10

Journal of Medicinal Chemistry

ApoptosisCell DeathMolecular BiologyNew SeriesFused Rings +15

Discovery of <i>N</i>-(4-Methoxyphenyl)-<i>N</i>,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration

Nilantha Sirisoma, Azra Pervin, Hong Zhang, +9

Journal of Medicinal Chemistry

Cell DeathPharmacotherapyPharmaceutical ChemistryMedicinal ChemistryEfficacious Anticancer Agent +14

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions

William Kemnitzer, Songchun Jiang, Yan Wang, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +11

Rates of cooling and denudation of the Early Penglai Orogeny, Taiwan, as assessed by fission-track constraints

Taixun Liu, Yue‐Gau Chen, Wen‐Shan Chen, +1

Tectonophysics

EngineeringEast Asian LanguagesGeologyFission-track ConstraintsPleistocene +5

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure–activity relationships of the 1- and 3-positions

William Kemnitzer, Jared Kuemmerle, Songchun Jiang, +7

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineNatural SciencesApoptosisCaspase-based High-throughput +9