DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Hiro Sato, Atsuko Niimi, Takaaki Yasuhara, +14

Nature Communications

Tumor BiologyGenome InstabilityCell RegulationPd-l1 ExpressionMedicine +11

Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

Tomoo Ogi, Siripan Limsirichaikul, René Overmeer, +11

Molecular Cell

Polymerase Chain ReactionGenome InstabilityTranscriptional RegulationChromatinDifferent Mechanisms +9

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Atsuko Niimi, Stephanie E. Brown, Simone Sabbioneda, +5

Proceedings of the National Academy of Sciences

ImmunologyMolecular BiologyReplication ForkCell ProliferationCell Cycle +18

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation

Mayu Isono, Atsuko Niimi, Takahiro Oike, +11

Cell Reports

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Catherine Green, Simone Sabbioneda, Nicola Crosetto, +6

Molecular Cell

Transcriptional RegulationNatural SciencesOligonucleotideDna ReplicationMolecular Biology +4

Inhibitors of the Proteasome Suppress Homologous DNA Recombination in Mammalian Cells

Yasuhiro Murakawa, Eiichiro Sonoda, Louise J. Barber, +9

Cancer Research

Palm Mutants in DNA Polymerases α and η Alter DNA Replication Fidelity and Translesion Activity

Atsuko Niimi, Siripan Limsirichaikul, Shonen Yoshida, +6

Molecular and Cellular Biology

Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy

Takahiro Oike, Atsuko Niimi, Noriyuki Okonogi, +10

Scientific Reports

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

Yoshihiko Hagiwara, Atsuko Niimi, Mayu Isono, +8

Oncotarget

Co-localization of chicken DNA topoisomerase IIα, but not β, with sites of DNA replication and possible involvement of a C-terminal region of α through its binding to PCNA

Atsuko Niimi, Noriyuki Suka, Masahiko Harata, +2

Chromosoma

ChromatinPossible InvolvementC-terminal RegionBiochemistryNatural Sciences +2