Wei Wu

Temsirolimus Activates Autophagy and Ameliorates Cardiomyopathy Caused by Lamin A/C Gene Mutation

Jason C. Choi, Antoine Muchir, Wei Wu et al. · Science Translational Medicine · 2012 · 211 citations · Full text

Cell Autophagy, Mitophagy, Heart Failure +14

MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-β signaling

Feng Lin, Juliet Morrison, Wei Wu et al. · Human Molecular Genetics · 2004 · 207 citations · Full text

Reporter Gene, Cellular Physiology, Signaling Pathway +16

Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Wei Wu, Antoine Muchir, Jian Shan et al. · Circulation · 2010 · 190 citations · Full text

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

Fanjun Meng, Dongdong Yao, Yang Shi et al. · Molecular Neurodegeneration · 2011 · 156 citations · Full text

ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Maria Chatzifrangkeskou, Caroline Le Dour, Wei Wu et al. · Human Molecular Genetics · 2016 · 103 citations · Full text