Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Wei Wu, Antoine Muchir, Jian Shan, Gisèle Bonne, Howard J. Worman

Circulation · 2010 · 190 citations · 38 references

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Abstract

Inhibitors of ERK and JNK signaling could potentially be used to treat humans with cardiomyopathy caused by LMNA mutations.

References

38