William D. Hoffman

Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock.

Charles Natanson, P. W. Eichenholz, Robert L. Danner et al. · The Journal of Experimental Medicine · 1989 · 567 citations · Full text

Heart Failure, Veterinary Research, Veterinary Microbiology +18

N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin.

Justin Cobb, Charles Natanson, William D. Hoffman et al. · The Journal of Experimental Medicine · 1992 · 249 citations · Full text

Pharmacotherapy, Mortality Rates, Oxidative Stress +16

Randomization in clinical trials of titrated therapies: Unintended consequences of using fixed treatment protocols*

Katherine J. Deans, Peter C. Minneci, Anthony F. Suffredini et al. · Critical Care Medicine · 2007 · 156 citations

The Posthospital Phase of Myocardial Infarction

Arthur J. Moss, John DeCamilla, FREDERICK ENGSTROM et al. · Circulation · 1974 · 116 citations · Full text

Heart Failure, Cardiovascular Disease, High Risk +12

Tumor necrosis factor challenges in canines: patterns of cardiovascular dysfunction

P. W. Eichenholz, P. Q. Eichacker, William D. Hoffman et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1992 · 113 citations

Heart Failure, Pathology, Veterinary Research +19