Bradycardia and Slowing of the Atrioventricular Conduction in Mice Lacking Ca _V 3.1/α _1G T-Type Calcium Channels

Matteo E. Mangoni, Achraf Traboulsie, Anne‐Laure Léoni, +11

Circulation Research

Cardiac MuscleRight AtriumCardiovascular FunctionCellular PhysiologySocial Sciences +16

Mouse Model of <i>SCN5A</i> -Linked Hereditary Lenegre’s Disease

Anne Royer, Toon A.B. van Veen, Sabrina Le Bouter, +16

Circulation

Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene <i>Scn5a</i>

Ming Lei, Catharine A. Goddard, Jie Liu, +11

The Journal of Physiology

Cardiac MuscleHeart FailureCardiovascular FunctionCellular PhysiologySocial Sciences +19

Variable Nav1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a+/− Mouse Model

Anne‐Laure Léoni, Bruno Gavillet, Jean‐Sébastien Rougier, +15

PLoS ONE

The G-protein–gated K+ channel, <i>IKACh</i>, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

Pietro Mesirca, Laurine Marger, Futoshi Toyoda, +12

The Journal of General Physiology

Cardiac MuscleSympathetic StimulationCardiovascular FunctionCellular PhysiologySocial Sciences +16

G protein-gated <i>I</i> _<i>KACh</i> channels as therapeutic targets for treatment of sick sinus syndrome and heart block

Pietro Mesirca, Isabelle Bidaud, François Briec, +12

Proceedings of the National Academy of Sciences

Chronic heart rate reduction remodels ion channel transcripts in the mouse sinoatrial node but not in the ventricle

Anne‐Laure Léoni, Céline Marionneau, Sophie Demolombe, +4

Physiological Genomics

Cardiac MuscleHeart FailureCardiovascular FunctionIon Channel SubunitsHyperpolarization (Biology) +18

Biological Pacemaker Engineered by Nonviral Gene Transfer in a Mouse Model of Complete Atrioventricular Block

Julien Piron, Khaï Le Quang, François Briec, +6

Molecular Therapy

Physicochemical and toxicological characterization of a new generic iron sucrose preparation

Thomas Meier, Patricia Schropp, Christian Pater, +3

Arzneimittelforschung

EngineeringIron MetabolismFood AnalysisIron Sucrose PreparationsToxicological Characterization +23

Historical control data for hematology parameters obtained from toxicity studies performed on different Wistar rat strains: Acceptable value ranges, definition of severity degrees, and vehicle effects

Marlies de Kort, Klaus Weber, Björn Wimmer, +4

Toxicology Research and Application

DiagnosisToxicology TestingVeterinary ResearchSingle OutliersLaboratory Animal Study +18