IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age

Hirotake Tsukamoto, Satoru Senju, Keiko Matsumura, +2

Nature Communications

Identification of a Novel Polymorphic Enhancer of the Human CYP3A4 Gene

Keiko Matsumura, Tetsuya Saito, Yoshiki Takahashi, +6

Molecular Pharmacology

Decreased coumarin 7-hydroxylase activities and CYP2A6 expression levels in humans caused by genetic polymorphism in CYP2A6 promoter region (CYP2A6*9)

Kazuma Kiyotani, Hiroshi Yamazaki, Masaki Fujieda, +11

Pharmacogenetics

Promoter RegionCoumarin 7-Hydroxylase ActivitiesMedicineGeneticsHuman Polymorphism +13

Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2

Koutaro Takamatsu, Tokunori Ikeda, Miwa Haruta, +7

Stem Cell Research

ImmunologyCell DeathTherapeuticsCulture MediumNeuroinflammation +17

CYP3A5 Contributes Significantly to CYP3A-mediated Drug Oxidations in Liver Microsomes from Japanese Subjects

Satoshi Yamaori, Hiroshi Yamazaki, Shunsuke Iwano, +6

Drug Metabolism and Pharmacokinetics

Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression

Hirotake Tsukamoto, Koji Fujieda, Masatoshi Hirayama, +9

Cancer Research

Therapeutic Effect of Human iPS-Cell–Derived Myeloid Cells Expressing IFN-β against Peritoneally Disseminated Cancer in Xenograft Models

Chihiro Koba, Miwa Haruta, Yusuke Matsunaga, +7

PLoS ONE

Molecular epidemiology of bovine leukemia virus associated with enzootic bovine leukosis in Japan

Keiko Matsumura, Emi Inoue, Yoshiaki Osawa, +1

Virus Research

Molecular EpidemiologyAnimal ScienceMedicinePathogenesisVeterinary Science +8

L233P mutation of the Tax protein strongly correlated with leukemogenicity of bovine leukemia virus

Emi Inoue, Keiko Matsumura, Norihiko Soma, +6

Veterinary Microbiology

Tax ProteinMedicineGeneticsPathologyVirology +6

Generation of a large number of functional dendritic cells from human monocytes expanded by forced expression of cMYC plus BMI1

Miwa Haruta, Yusuke Tomita, Yuya Imamura, +5

Human Immunology

InflammationHuman MonocytesGranulocyteImmune Cell DevelopmentImmunology +8