Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment

Hirotake Tsukamoto, Koji Fujieda, Azusa Miyashita, +7

Cancer Research

Association of Probiotic <i>Clostridium butyricum</i> Therapy with Survival and Response to Immune Checkpoint Blockade in Patients with Lung Cancer

Yusuke Tomita, Tokunori Ikeda, Shinya Sakata, +8

Cancer Immunology Research

Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy

Satoru Senju, Miwa Haruta, Kimio Matsumura, +6

Gene Therapy

Regenerative MedicineCell TherapyInduced Pluripotent Stem CellCellular TherapiesMedicine +11

Association between HLA gene polymorphisms and mortality of COVID‐19: An in silico analysis

Yusuke Tomita, Tokunori Ikeda, Ryo Sato, +1

Immunity Inflammation and Disease

Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells

Satoru Senju, Miwa Haruta, Yusuke Matsunaga, +6

Stem Cells

Dual Effects of TRAIL in Suppression of Autoimmunity: The Inhibition of Th1 Cells and the Promotion of Regulatory T Cells

Tokunori Ikeda, Shinya Hirata, Satoshi Fukushima, +5

The Journal of Immunology

T-regulatory CellImmunologyImmune RegulationRegulatory T CellsCd4 T Cell Responses +18

Disorder of Coagulation-Fibrinolysis System: An Emerging Toxicity of Anti-PD-1/PD-L1 Monoclonal Antibodies

Ryo Sato, Kosuke Imamura, Shinya Sakata, +13

Journal of Clinical Medicine

<i>Clostridium butyricum</i> therapy restores the decreased efficacy of immune checkpoint blockade in lung cancer patients receiving proton pump inhibitors

Yusuke Tomita, Yoshihiko Goto, Shinya Sakata, +14

OncoImmunology

TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells

Miwa Haruta, Yusuke Tomita, Akira Yuno, +7

Gene Therapy

Unlimited Cell SourceImmunologyAntigen ProcessingDendritic Cell BiologyCellular Immune Response +4

Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2

Koutaro Takamatsu, Tokunori Ikeda, Miwa Haruta, +7

Stem Cell Research

ImmunologyCell DeathTherapeuticsCulture MediumNeuroinflammation +17