Synthesis of Thrombin Inhibitor DuP 714

John Wityak, Richard A. Earl, Matthew M. Abelman, +6

The Journal of Organic Chemistry

Altmetric Attention ScorePharmacotherapyChemical BiologyThrombosisMedicinal Chemistry +16

Discovery of Potent Isoxazoline Glycoprotein IIb/IIIa Receptor Antagonists

John Wityak, Thais M. Sielecki, Donald Pinto, +10

Journal of Medicinal Chemistry

ThrombopoiesisThrombosisMedicinal ChemistryBiochemistryBlood Platelet +12

Synthesis of amphotericin B. 1. Fragment A of the aglycon

Satoru Masamune, Philip Ma, Hiroshi Okumoto, +2

The Journal of Organic Chemistry

Bioorganic ChemistryAltmetric Attention ScoreBibliometricsChemistryChemical Biology +17

Synthesis of Cyclic and Acyclic β-Amino Acids via Chelation-Controlled 1,3-Dipolar Cycloaddition

Roger Hanselmann, Jiacheng Zhou, Philip Ma, +1

The Journal of Organic Chemistry

An Efficient Large-Scale Process for the Human Leukocyte Elastase Inhibitor, DMP 777¹

Louis Storace, Luigi Anzalone, Pat N. Confalone, +13

Organic Process Research & Development

Chiral AcidEfficient Large-scale ProcessImmunologyOrganic ChemistryChemistry +17

Mutations in Signal Sequence Cleavage Domain of Preproparathyroid Hormone Alter Protein Translocation, Signal Sequence Cleavage, and Membrane-Binding Properties

Kristine M. Wiren, Lionel B. Ivashkiv, Philip Ma, +3

Molecular Endocrinology

Efficient Preparation of a Key Intermediate in the Synthesis of Roxifiban by Enzymatic Dynamic Kinetic Resolution on Large Scale

Jaan A. Pesti, Jinguao Yin, Linhua Zhang, +13

Organic Process Research & Development

Bioorganic ChemistryKey IntermediateEngineeringChemical TransformationKinetic Resolution +22

Computation of vicinal coupling constants in tetra- and hexa-alditol peracetates using molecular mechanics. A rational approach to conformational analysis in solution

Satoru Masamune, Philip Ma, Richard E. Moore, +3

Journal of the Chemical Society Chemical Communications

Vicinal Coupling ConstantsMagnetic ResonanceRational ApproachComputational ChemistryChemistry +14

An Agent-Based Modeling and Virtual Reality Application Using Distributed Simulation: Case of a COVID-19 Intensive Care Unit

Jalal Possik, Ali Asgary, Adriano O. Solis, +11

IEEE Transactions on Engineering Management

EngineeringUnity PlatformVirtual Reality SimulationSimulationIntelligent Systems +18

An analysis of messages sent between nurses and physicians in deteriorating internal medicine patients to help identify issues in failures to rescue

Hannah J. Wong, Rachel Bierbrier, Philip Ma, +3

International Journal of Medical Informatics

NursingPalliative CarePrimary CareChief ComplaintPatient Safety +6